Inflammation articles within Nature Materials

Featured

• Article | 11 July 2022

  Mechanical checkpoint regulates monocyte differentiation in fibrotic niches

  Myelofibrosis causes a pathological remodelling of the bone marrow, which becomes stiffer and more elastic, thus promoting the proliferation of proinflammatory monocytes and their differentiation into dendritic cells.

  • Kyle H. Vining
  • , Anna E. Marneth
  •  & David J. Mooney

• News & Views | 22 July 2019

  Limiting biomaterial fibrosis

  Crystallized anti-inflammatory drugs have been shown to inhibit fibrosis on the surface of a number of devices over a long-term period following implantation in rodents and non-human primates.

  • Ruud A. Bank

• News & Views | 19 February 2019

  Induction of sterile type 2 inflammation

  Microparticle debris from prosthetic implants has been shown to induce a type 2 inflammatory response through a Bruton’s tyrosine kinase-dependent signalling pathway.

  • Dimitri A. de Kouchkovsky
  • , Sourav Ghosh
  •  & Carla V. Rothlin

• News & Views | 23 November 2018

  Control by cell size

  Macrophage confinement reduces the ‘late’ inflammatory gene response to lipopolysaccharide through myocardin-related transcription factor, an actin-binding transcription factor.

  • Wendy F. Liu

• Article | 22 October 2018

  Spatial confinement downsizes the inflammatory response of macrophages

  Physical confinement of macrophages is shown to down-regulate pro-inflammatory gene transcription, lowering pro-inflammatory macrophage activation and phagocytic potential.

  • Nikhil Jain
  •  & Viola Vogel