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| Open AccessMultimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation
- Kyle Ford
- , Brenton P. Munson
- & Trey Ideker
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| Open AccessPET-CT and RNA sequencing reveal novel targets for acupuncture-induced lowering of blood pressure in spontaneously hypertensive rats
- Jing Li
- , Chong Peng
- & Xinsheng Lai
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| Open AccessA CRISPR-Cas9 based shuffle system for endogenous histone H3 and H4 combinatorial mutagenesis
- Yu Fu
- , Zhenglin Zhu
- & Yueping Zhang
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| Open AccessGenome targeting by hybrid Flp-TAL recombinases
- Eugenia Voziyanova
- , Feng Li
- & Yuri Voziyanov
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| Open AccessExploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach
- Viktor Vernyik
- , Ildikó Karcagi
- & György Pósfai
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| Open AccessGeneration of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts
- Victoire Cardot-Ruffino
- , Véronique Chauvet
- & Laurent Bartholin
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| Open AccessGenome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells
- Joana Ferreira da Silva
- , Sejla Salic
- & Joanna I. Loizou
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| Open AccessProbing the Behaviour of Cas1-Cas2 upon Protospacer Binding in CRISPR-Cas Systems using Molecular Dynamics Simulations
- Hua Wan
- , Jianming Li
- & Jianping Hu
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| Open AccessA Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease
- Yue Ren
- , Etsuko Sekine-Kondo
- & Hiroshi Watarai
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| Open AccessInsertion of a knockout-first cassette in Ampd1 gene leads to neonatal death by disruption of neighboring genes expression
- Yongcheng Pan
- , Lusi Zhang
- & Jia-Da Li
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| Open AccessCRISPR-PCS: a powerful new approach to inducing multiple chromosome splitting in Saccharomyces cerevisiae
- Yu Sasano
- , Koki Nagasawa
- & Satoshi Harashima
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| Open AccessThe no-SCAR (
S carlessC as9A ssistedR ecombineering) system for genome editing in Escherichia coli- Chris R. Reisch
- & Kristala L. J. Prather
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| Open AccessMethod of preparing an equimolar DNA mixture for one-step DNA assembly of over 50 fragments
- Kenji Tsuge
- , Yukari Sato
- & Mitsuhiro Itaya
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| Open AccessIdentification of germline transcriptional regulatory elements in Aedes aegypti
- Omar S. Akbari
- , Philippos A. Papathanos
- & Bruce A. Hay