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| Open AccessStructural basis of redox-dependent substrate binding of protein disulfide isomerase
- Maho Yagi-Utsumi
- , Tadashi Satoh
- & Koichi Kato
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Article
| Open AccessSlow mitochondrial repair of 5′-AMP renders mtDNA susceptible to damage in APTX deficient cells
- Mansour Akbari
- , Peter Sykora
- & Vilhelm A. Bohr
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| Open AccessRegulation of PLCβ2 by the electrostatic and mechanical properties of lipid bilayers
- Alessia Arduin
- , Piers R. J. Gaffney
- & Oscar Ces
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| Open AccessCrystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases
- Junji Hayashi
- , Shota Inoue
- & Haruhiko Sakuraba
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| Open AccessMechanistic studies of a novel C-S lyase in ergothioneine biosynthesis: the involvement of a sulfenic acid intermediate
- Heng Song
- , Wen Hu
- & Pinghua Liu
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| Open AccessRedox Linked Flavin Sites in Extracellular Decaheme Proteins Involved in Microbe-Mineral Electron Transfer.
- Marcus J. Edwards
- , Gaye F. White
- & Thomas A. Clarke
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Article
| Open AccessThe HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling
- Gábor M. Harami
- , Nikolett T. Nagy
- & Mihály Kovács
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| Open AccessA novel cysteine desulfurase influencing organosulfur compounds in Lentinula edodes
- Ying Liu
- , Xiao-Yu Lei
- & Wen Huang
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| Open AccessStructural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity
- Yasumitsu Sakamoto
- , Yoshiyuki Suzuki
- & Nobutada Tanaka
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Article
| Open AccessMelanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5a
- Lin-Lin Yao
- , Qing-Juan Cao
- & Xiang-dong Li
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Article
| Open AccessStructural Insights into Substrate Specificity of Feruloyl-CoA 6’-Hydroxylase from Arabidopsis thaliana
- Xinxiao Sun
- , Dayong Zhou
- & Yajun Yan
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Article
| Open AccessAuto-inhibitory Mechanism of the Human Mitochondrial RNase P Protein Complex
- Fengzhi Li
- , Xiaofen Liu
- & Yuequan Shen
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Article
| Open AccessA Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism
- Jana Indra Führing
- , Johannes Thomas Cramer
- & Roman Fedorov
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Article
| Open AccessStructure and function of a Clostridium difficile sortase enzyme
- Christopher J. Chambers
- , April K. Roberts
- & K. Ravi Acharya
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Article
| Open AccessMechanism of Action of Thalassospiramides, A New Class of Calpain Inhibitors
- Liang Lu
- , Michael J. Meehan
- & Pei-Yuan Qian
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Article
| Open AccessStructural Basis for Substrate-specific Acetylation of Nα-acetyltransferase Ard1 from Sulfolobus solfataricus
- Yu-Yung Chang
- & Chun-Hua Hsu
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Article
| Open AccessThe catalytic role of the M2 metal ion in PP2Cα
- Chang Pan
- , Jun-yi Tang
- & Jin-peng Sun
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Article
| Open AccessEfficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies
- Yan-Bin Teng
- , Hui Jing
- & Quan Hao
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Article
| Open AccessCrystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes
- Hackwon Do
- , Soo Jin Kim
- & Jun Hyuck Lee
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Article
| Open AccessHow water molecules affect the catalytic activity of hydrolases - A XANES study of the local structures of peptide deformylase
- Peixin Cui
- , Yu Wang
- & Ziyu Wu
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Article
| Open AccessStructural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase
- Tong Zhu
- , Tadashi Satoh
- & Koichi Kato
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Article
| Open Accessgp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains
- Weixiao Liu
- , Yongliang Shang
- & Wei Li
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Article
| Open AccessStructure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum
- Wenting Liu
- , Xinxin Feng
- & Rey-Ting Guo
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Article
| Open AccessSingle-molecule real-time detection of telomerase extension activity
- Helen Hwang
- , Patricia Opresko
- & Sua Myong
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Article
| Open AccessDNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases
- Neil H. Thomson
- , Sergio Santos
- & Anthony Maxwell
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Article
| Open AccessDermcidin isoform-2 induced nullification of the effect of acetyl salicylic acid in platelet aggregation in acute myocardial infarction
- Sarbashri Bank
- , Pradipta Jana
- & A. K. Sinha
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Article
| Open AccessCell-secreted Flavins Bound to Membrane Cytochromes Dictate Electron Transfer Reactions to Surfaces with Diverse Charge and pH
- Akihiro Okamoto
- , Shafeer Kalathil
- & Kenneth H. Nealson
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Article
| Open AccessDark-operative protochlorophyllide oxidoreductase generates substrate radicals by an iron-sulphur cluster in bacteriochlorophyll biosynthesis
- Jiro Nomata
- , Toru Kondo
- & Yuichi Fujita
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Article
| Open AccessS46 Peptidases are the First Exopeptidases to be Members of Clan PA
- Yasumitsu Sakamoto
- , Yoshiyuki Suzuki
- & Nobutada Tanaka
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Article
| Open AccessIdentification of the Catalytic Triad of Family S46 Exopeptidases, Closely Related to Clan PA Endopeptidases
- Yoshiyuki Suzuki
- , Yasumitsu Sakamoto
- & Wataru Ogasawara
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Article
| Open AccessThe structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis
- Jie Li
- , Cheng Wang
- & Jiahai Zhou
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Article
| Open AccessCharacterization of cleavage intermediate and star sites of RM.Tth111II
- Zhenyu Zhu
- , Shengxi Guan
- & Shuang-yong Xu
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Article
| Open AccessThe antimalarial drug quinine interferes with serotonin biosynthesis and action
- Farida Islahudin
- , Sarah M. Tindall
- & Simon V. Avery
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Article
| Open AccessA molecular pathway for the egress of ammonia produced by nitrogenase
- Ian Dance
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Article
| Open AccessHorseradish Peroxidase Inactivation: Heme Destruction and Influence of Polyethylene Glycol
- Liang Mao
- , Siqiang Luo
- & Junhe Lu
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Article
| Open AccessQuantitative full time course analysis of nonlinear enzyme cycling kinetics
- Wenxiang Cao
- & Enrique M. De La Cruz
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Article
| Open AccessConferring the ability to utilize inorganic polyphosphate on ATP-specific NAD kinase
- Yusuke Nakamichi
- , Aya Yoshioka
- & Kousaku Murata
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Article
| Open AccessSmall molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent
- Amaravadhi Harikishore
- , Makhtar Niang
- & Ho Sup Yoon
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Article
| Open AccessImpact of Site-Directed Mutant Luciferase on Quantitative Green and Orange/Red Emission Intensities in Firefly Bioluminescence
- Yu Wang
- , Hidefumi Akiyama
- & Toru Nakatsu
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Article
| Open AccessRegulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase
- Anshika Singhal
- , Gunjan Arora
- & Yogendra Singh
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Article
| Open AccessThe role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89
- Lei Yuwen
- , Feng-Li Zhang
- & Zhi-Yong Li
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Article
| Open AccessHuman castration resistant prostate cancer rather prefer to decreased 5α-reductase activity
- Takeo Kosaka
- , Akira Miyajima
- & Mototsugu Oya
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| Open AccesshDbr1 is a nucleocytoplasmic shuttling protein with a protein phosphatase-like motif essential for debranching activity
- Naoyuki Kataoka
- , Izumi Dobashi
- & Mutsuhito Ohno