DNA nanotechnology articles within Nature Materials

Featured

  • Article |

    Limited datasets hinder the accurate prediction of DNA origami structures. A data-driven and physics-informed approach for model training is presented using a graph neural network to facilitate the rapid virtual prototyping of DNA-based nanostructures.

    • Chien Truong-Quoc
    • , Jae Young Lee
    •  & Do-Nyun Kim

  • Article |

    The rational design and assembly of colloidal quasicrystals is achieved by exploring the hybridization of nanoscale decahedra nanoparticles functionalized with DNA linkers.

    • Wenjie Zhou
    • , Yein Lim
    •  & Chad A. Mirkin

  • Article |

    Symmetry breaking in colloidal crystals is achieved with DNA-grafted programmable atom equivalents and complementary electron equivalents, whose interactions are tuned to create anisotropic crystalline precursors with well-defined coordination geometries that assemble into distinct low-symmetry crystals.

    • Shunzhi Wang
    • , Sangmin Lee
    •  & Chad A. Mirkin

  • Editorial |

    DNA is much more than the genetic information it carries. It is a versatile material for creating systems with tailor-made functionalities that are having an important impact in emerging technologies.

  • News & Views |

    Elaborately designed DNA icosahedral shells cage intact virions to effectively protect host cells from viral infections.

    • Neha Chauhan
    •  & Xing Wang

  • News & Views |

    Data-encoded DNA sequences have been encapsulated in barcoded silica beads for a random access storage system without PCR amplification.

    • Luca Piantanida
    •  & William L. Hughes

  • Article |

    Epitaxially grown 3D DNA masks with prescribed geometry, pitch and size improve the resolution of reactive ion etching-based nanolithography, scaling the line pitch down to 16.2 nm and the critical dimension size to 7.2 nm.

    • Jie Shen
    • , Wei Sun
    •  & Peng Yin

  • News & Views |

    An elaborate DNA origami tubular nanodevice encapsulating antigens and adjuvants protects mice from cancer through tumour-specific immunomodulation.

    • Hongjun Li
    •  & Zhen Gu

  • Article |

    A DNA nanodevice vaccine has been developed and utilized to stimulate a tumour-specific cytotoxic T lymphocyte response in vivo, leading to the inhibition of tumour growth as well as prevention of metastasis.

    • Shaoli Liu
    • , Qiao Jiang
    •  & Baoquan Ding

  • News & Views |

    Programmable DNA building blocks hosting diverse nano-objects assemble into three-dimensional nanoparticle lattices whose geometry is determined by the shape and valence of the DNA block.

    • Veikko Linko
    •  & Mauri A. Kostiainen

  • Comment |

    The complexity of DNA-programmed nanoparticle assemblies has reached an unprecedented level owing to recent advances that enable delicate and comprehensive control over the formation of DNA bonds.

    • Shuoxing Jiang
    • , Fei Zhang
    •  & Hao Yan

  • Article |

    Single-stranded DNA encoders containing polyadenine domains endow colloidal gold nanoparticles with programmable bond valence, orthogonality and reconfigurability, thus achieving post-synthetic control over colloidal structures.

    • Guangbao Yao
    • , Jiang Li
    •  & Chunhai Fan

  • Article |

    DNA-based nanodevices with decision-making and information-processing capabilities have been developed. Here, a DNA-based molecular navigation system that explores a DNA origami maze for all possible solutions is reported.

    • Jie Chao
    • , Jianbang Wang
    •  & Chunhai Fan

  • News & Views |

    Dye molecules are shown to assemble into J-aggregate arrays by sequence-specific organization in the minor groove of DNA duplex sequences. Energy transfer through these structures displays the hallmarks of coherent coupling over distances that exceed those of conventional dipole-coupling processes.

    • Marcel P. Bruchez

  • Editorial |

    The versatility of DNA linkers as selective binders is accelerating the rational design of the assembly of nanoparticle crystals with unprecedented structural complexity.

  • News & Views |

    The structure of crystals made of DNA-bridged nanoparticles can be selectively switched between various lattices by reprogramming the DNA-mediated interactions between the nanoparticles.

    • Erika Eiser

  • News & Views |

    Improved control over the shape of nanoparticles and the interactions between them allows the rational construction of intricate microscale assemblies.

    • Jean-Philippe Sobczak
    •  & Hendrik Dietz

  • Commentary |

    Advances in the control of the shape, bonding direction and valency of DNA-coated nanoparticles allow the synthesis of nanoparticle crystallites of ever increasing complexity.

    • Bert Nickel
    •  & Tim Liedl

  • Letter |

    Until now, it has not been possible to switch chirality in plasmonic nanostructures at will and repeatedly. Now, thanks to DNA-regulated conformational changes, reconfigurable 3D plasmonic metamolecules with switchable chirality have been created.

    • Anton Kuzyk
    • , Robert Schreiber
    •  & Na Liu

  • News & Views |

    DNA-capped nanoparticles crystallize into uniform microcrystals of Wulff polyhedra when cooled slowly through the melting temperature of the DNA linkers.

    • Shogo Hamada
    • , Shawn J. Tan
    •  & Dan Luo

  • News & Views |

    A general approach for decorating nanoparticles with a highly dense shell of DNA linkers expands the range of building blocks that can be used for DNA-mediated nanoparticle self-assembly.

    • Ulrich Simon

  • News & Views |

    Self-assembled barrel-like DNA nanostructures carrying active payloads and pre-programmed with logic operations to reconfigure in response to cell-surface cues can trigger a variety of intracellular functions.

    • Johann Elbaz
    •  & Itamar Willner

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