Diagnostics articles within Nature Materials

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• Article | 27 May 2019

  Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

  Chemiluminescent molecular renal probes have been developed and are shown to be capable of non-invasive real-time imaging of early-stage oxidative stress biomarkers of drug-induced acute kidney injury, and high renal clearance.

  • Jiaguo Huang
  • , Jingchao Li
  •  & Kanyi Pu

• Perspective | 18 April 2019

  Exploiting machine learning for end-to-end drug discovery and development

  This Perspective describes the application of machine learning models in the design, synthesis and characterisation of molecules at different stages in the drug discovery and development process.

  • Sean Ekins
  • , Ana C. Puhl
  •  & Alex M. Clark