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Article
| Open Access
Real-time signal processing via chemical reactions for a microfluidic molecular communication system
The use of electronic devices to process electrical signals in molecular communications can hardly realize its potential for various applications. Here, the authors report on chemical concentration signal processing in real time and digital signal transmission over distances.
- Vivien Walter
- , Dadi Bi
- & Yansha Deng
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Article
| Open Access
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design
G protein-coupled receptors (GPCRs) are a critical target in modern drug development across a wide range of indications. Here the authors provide a comprehensive characterization of a typical GPCR, the angiotensin II (AngII) type 1 receptor (AT1R), and provide insight into its activation mechanism that suggest avenues for the design of allosteric GPCR modulators.
- Shaoyong Lu
- , Xinheng He
- & Jian Zhang
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Article
| Open Access
Networking chemical robots for reaction multitasking
Distributing a reaction workload across laboratories can solve chemical problems more efficiently, but it is challenging to develop viable hardware and software. Here, the authors present an internet-connected network of cheap robots that can perform chemical reactions and share outcomes in real time, demonstrating a digitized approach to chemical collaboration.
- Dario Caramelli
- , Daniel Salley
- & Leroy Cronin
Mechanistic exploration of polytetrafluoroethylene thermal plasma gasification through multiscale simulation coupled with experimental validation