Featured
-
-
Article
| Open AccessIdentification of cancer risk groups through multi-omics integration using autoencoder and tensor analysis
- Ali Braytee
- , Sam He
- & Ali Anaissi
-
Article
| Open AccessMiR-1976/NCAPH/P65 axis inhibits the malignant phenotypes of lung adenocarcinoma
- Peiluo Huang
- , Hongtao Zhao
- & Juan Du
-
Article
| Open AccessEstablishment, characterization, and genetic profiling of patient-derived osteosarcoma cells from a patient with retinoblastoma
- Patcharawadee Thongkumkoon
- , Apiwat Sangphukieo
- & Parunya Chaiyawat
-
Article
| Open AccessElucidating immunological characteristics of the adenoma-carcinoma sequence in colorectal cancer patients in South Korea using a bioinformatics approach
- Jaeseung Song
- , Daeun Kim
- & Wonhee Jang
-
Article
| Open AccessPan-cancer analysis reveals correlation between RAB3B expression and tumor heterogeneity, immune microenvironment, and prognosis in multiple cancers
- Xu-Sheng Liu
- , Ya-Lan Chen
- & Zhi-Jun Pei
-
Article
| Open AccessEssentiality, protein–protein interactions and evolutionary properties are key predictors for identifying cancer-associated genes using machine learning
- Amro Safadi
- , Simon C. Lovell
- & Andrew J. Doig
-
Article
| Open AccessNew treatment alternatives for primary and metastatic colorectal cancer by an integrated transcriptome and network analyses
- Caner Karaca
- , Ezgi Demir Karaman
- & Yasemin Basbinar
-
Article
| Open AccessA chromosome-scale fishing cat reference genome for the evaluation of potential germline risk variants
- Rachel A. Carroll
- , Edward S. Rice
- & Wesley C. Warren
-
Article
| Open AccessThe impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities
- Ruotian Huang
- , M. S. Riana Bornman
- & Vanessa M. Hayes
-
Article
| Open AccessIdentification of molecular subtypes and a prognostic signature based on m6A/m5C/m1A-related genes in lung adenocarcinoma
- Yu Zhang
- , Qiuye Jia
- & Li Bian
-
Article
| Open AccessInvestigating diagnostic potential of long non-coding RNAs in head and neck squamous cell carcinoma using TCGA database and clinical specimens
- Ting Lan
- , Yuxiang Yan
- & Lincan Ding
-
Article
| Open AccessCRISPR/Cas9 targeting of passenger single nucleotide variants in haploinsufficient or essential genes expands cancer therapy prospects
- Hakhyun Kim
- , Jang Hee Han
- & Hyun Seok Kim
-
Article
| Open AccessExtend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project
- Binsheng Gong
- , Dan Li
- & Joshua Xu
-
Article
| Open AccessClinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
- Kevin J. Tam
- , Liangliang Liu
- & Christopher J. Ong
-
Article
| Open AccessSingle-cell RNA sequencing unveils tumor heterogeneity and immune microenvironment between subungual and plantar melanoma
- Panpan Wang
- , Yangyang Ma
- & Ping Wang
-
Article
| Open AccessPrediction uncertainty estimates elucidate the limitation of current NSCLC subtype classification in representing mutational heterogeneity
- Andrei Puiu
- , Carlos GĂłmez Tapia
- & Matthias Siebert
-
Article
| Open AccessIdentification of expression profiles and prognostic value of RFCs in colorectal cancer
- Md Misbah
- , Manoj Kumar
- & Mymoona Akhtar
-
Article
| Open AccessChallenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma
- Takahide Nejo
- , Lin Wang
- & Hideho Okada
-
Article
| Open AccessPolygenic risk score-based prediction of breast cancer risk in Taiwanese women with dense breast using a retrospective cohort study
- Chih-Chiang Hung
- , Sin-Hua Moi
- & Chi-Cheng Huang
-
Article
| Open AccessIdentifying microRNAs associated with tumor immunotherapy response using an interpretable machine learning model
- Dong-Yeon Nam
- & Je-Keun Rhee
-
Article
| Open AccessPrognostic mutation signature would serve as a potential prognostic predictor in patients with diffuse large B-cell lymphoma
- Shih-Feng Cho
- , Tsung-Jang Yeh
- & Sin-Hua Moi
-
Article
| Open AccessA comprehensive analysis and experimental validation of TK1 in uterine corpus endometrial carcinoma
- Yiqing Sun
- , Kaiwen Zhang
- & Yingmei Wang
-
Article
| Open AccessTumor location matters, next generation sequencing mutation profiling of left-sided, rectal, and right-sided colorectal tumors in 552 patients
- Izabela Ciepiela
- , Magdalena Szczepaniak
- & Artur Kowalik
-
Article
| Open AccessComprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer
- Dan-yang Chen
- , Yang-yang Zhang
- & Meng Zhang
-
Article
| Open AccessIntegrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers
- Haishun Qu
- , Jie Jiang
- & Yijue Qin
-
Article
| Open AccessTRIP6 a potential diagnostic marker for colorectal cancer with glycolysis and immune infiltration association
- Xu-Sheng Liu
- , Yu-Xuan Chen
- & Zhi-Jun Pei
-
Article
| Open AccessGenetic variants associated with osteosarcoma risk: a systematic review and meta-analysis
- Omneya Hassanain
- , Mahmoud Alaa
- & Ahmed M. El Ghoneimy
-
Article
| Open AccessPan-caner analysis identifies PSMA7 as a targets for amplification at 20q13.33 in tumorigenesis
- Guangying Sheng
- , Fuyu Li
- & Kankan Wang
-
Article
| Open AccessDEEPOMICS FFPE, a deep neural network model, identifies DNA sequencing artifacts from formalin fixed paraffin embedded tissue with high accuracy
- Dong-hyuk Heo
- , Inyoung Kim
- & Seong-Eui Hong
-
Article
| Open AccessEstablish a novel tumor budding-related signature to predict prognosis and guide clinical therapy in colorectal cancer
- Qixin Li
- , Gaixia Liu
- & Yinnan Chen
-
Article
| Open AccessEmpirical Bayes single nucleotide variant-calling for next-generation sequencing data
- Ali Karimnezhad
- & Theodore J. Perkins
-
Article
| Open AccessDeveloping a prognosis and chemotherapy evaluating model for colon adenocarcinoma based on mitotic catastrophe-related genes
- Yinglei Liu
- , Yamin Zhao
- & Hongjian Chen
-
Article
| Open AccessAnoikis related genes may be novel markers associated with prognosis for ovarian cancer
- Chen Yang
- , LuChao Zhu
- & Qin Lin
-
Article
| Open AccessLncRNA SOX9-AS1 triggers a transcriptional program involved in lipid metabolic reprogramming, cell migration and invasion in triple-negative breast cancer
- Mireya Cisneros-Villanueva
- , Marco Antonio Fonseca-Montaño
- & Alfredo Hidalgo-Miranda
-
Article
| Open AccessPIEZO2 expression is an independent biomarker prognostic for gastric cancer and represents a potential therapeutic target
- Yun-Chao Zhang
- , Min Yang
- & Jun Shi
-
Article
| Open AccessIdentification of an inflammation-related risk signature for prognosis and immunotherapeutic response prediction in bladder cancer
- Yanjun Wang
- , Yi Tang
- & Kai Yao
-
Article
| Open AccessSLMO2 is a potential prognostic and immunological biomarker in human pan-cancer
- Xiong Liu
- , Renming Yuan
- & Guangqiang Li
-
Article
| Open AccessUncovering hidden cancer self-dependencies through analysis of shRNA-level dependency scores
- Zohreh Toghrayee
- & Hesam Montazeri
-
Article
| Open AccessDevelopment and validation of a novel lysosome-related LncRNA signature for predicting prognosis and the immune landscape features in colon cancer
- Fengming Li
- , Wenyi Wang
- & Juqin Zheng
-
Article
| Open AccessWhole‑exome sequencing reveals Lewis lung carcinoma is a hypermutated Kras/Nras–mutant cancer with extensive regional mutation clusters in its genome
- Quan He
- , Cuirong Sun
- & Yuanjiang Pan
-
Article
| Open AccessMAD2L2, a key regulator in ovarian cancer and promoting tumor progression
- Kejun Xu
- , Xiaojiao Zheng
- & Huiqing Ding
-
Article
| Open AccessCharacterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro analysis
- Nafiseh Erfanian
- , Saeed Nasseri
- & Mohammad Hassan Namaei
-
Article
| Open AccessAssociation between copy number alterations estimated using low-pass whole genome sequencing of formalin-fixed paraffin-embedded prostate tumor tissue and cancer-specific clinical parameters
- Paul Vinu Salachan
- , Benedicte Parm Ulhøi
- & Karina Dalsgaard Sørensen
-
Article
| Open AccessDebiased inference for heterogeneous subpopulations in a high-dimensional logistic regression model
- Hyunjin Kim
- , Eun Ryung Lee
- & Seyoung Park
-
Article
| Open AccessSmall-scale mutations are infrequent as mechanisms of resistance in post-PARP inhibitor tumour samples in high grade serous ovarian cancer
- Nikki L. Burdett
- , Madelynne O. Willis
- & Elizabeth L. Christie
-
Article
| Open AccessLow incidence of microsatellite instability in gastric cancers and its association with the clinicopathological characteristics: a comparative study
- Fateme Fooladi Talari
- , Ali Bozorg
- & Kaveh Baghaei
-
Article
| Open AccessDeep learning-enabled breast cancer endocrine response determination from H&E staining based on ESR1 signaling activity
- Chun Wai Ng
- & Kwong-Kwok Wong
-
Article
| Open AccessNucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
- Aurel Prosz
- , Haohui Duan
- & Zoltan Szallasi
-
Article
| Open AccessRevealing the potential of necroptosis-related genes in prognosis, immune characteristics, and treatment strategies for head and neck squamous cell carcinoma
- Junhua Cao
- , Congxiao Wu
- & Ximei Wang