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Water brings order
Measurements of the structure and organization of intact bone samples show that water plays a significant role in orienting bone apatite crystals, and that such ordering is mediated by an amorphous mineral coating layer.
- Melinda Duer
- & Arthur Veis
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Article |
The predominant role of collagen in the nucleation, growth, structure and orientation of bone apatite
Calcium-rich non-collagenous proteins in the extracellular matrix of bone are believed to be involved in the different steps of bone mineralization. It is now shown that in the absence of these proteins collagen can initiate and orient growing apatite crystals in vitro, and influence both their structural characteristics on the atomic scale and their larger-scale three-dimensional distribution in bone.
- Yan Wang
- , Thierry Azaïs
- & Nadine Nassif