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Visualization of chromosome territories by fluorescence in situ hybridization


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Visualization of chromosome territories by fluorescence in situ hybridization
(A) Chromosome territories (green) in liver cell nuclei (blue). (B) Visualization of multiple chromosomes reveals spatial patterns of organization. Chromosomes 12 (red), 14 (blue) and 15 (green) form a cluster in mouse lymphocytes.

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Chromosomes occupy specific regions of a nucleus, called "chromosome territories." These subdomains might be doing much more than just keeping everything organized.

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