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Chromosomal profiles of DNA methylation in colon cancer cells

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Chromosomal profiles of DNA methylation in colon cancer cells
Methylation profile in primary fibroblasts (red) and SW48 cancer cells (green) over a 10-Mb window on chromosome 3q. The RefSeq gene annotations below the graph illustrate that the region of extensive hypomethylation in SW48 cells coincides with a gene-poor domain.

This image is linked to the following Scitable pages:

Epigenomics: The New Tool in Studying Complex Diseases

Identical twins often develop different characteristics, even though they carry the same sequence of DNA nucleotides. How can this be? The answer lies in epigenomics.

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