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Volume 21 Issue 5, May 2023

Soil viruses, inspired by the Review on p296.

Cover design: Philip Patenall.

Research Highlights

  • This new study reports that a fungal ectosymbiont metabolizes resin monoterpenes of the host tree and that the volatile products possibly function as cues for beetles to locate breeding sites with beneficial fungal symbionts.

    • Andrea Du Toit
    Research Highlight

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  • This study reveals a role of contractile injection systems in regulated cell death and developmental processes.

    • Andrea Du Toit
    Research Highlight
  • This study reports that some bacterial species of the Lachnospiraceae family can suppress colorectal cancer progression by modulating CD8+ T cell immune surveillance activity.

    • Agustina Taglialegna
    Research Highlight
  • A recent study uncovered a relationship between sensory neurons and immune cells in the meninges that facilitates brain invasion by two Streptococcus species and the development of meningitis in mice.

    • Ashley York
    Research Highlight
  • This study analysed sorption, stability and persistence of SARS-CoV-2 RNA in sewers.

    • Andrea Du Toit
    Research Highlight
  • This study reports how fluid flow is linked to changes in gene expression in bacterial pathogens.

    • Andrea Du Toit
    Research Highlight
  • This study reports that heat treatment can increase the bactericidal activity of aminoglycosides against multi-drug resistant pathogens.

    • Agustina Taglialegna
    Research Highlight
  • This study shows the development of a chimeric dengue virus bivalent vaccine that generated serotype-specific neutralizing antibodies in vivo.

    • Agustina Taglialegna
    Research Highlight
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News & Analysis

  • This Genome Watch explores how large-scale microbiome studies are facilitating discoveries in bacteriophage biology and functional capabilities that are prime for translation towards advances in biotechnology and biotherapeutics.

    • Andre Mu
    • Trevor D. Lawley
    Genome Watch
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Reviews

  • In this Review, Blair, Webber and colleagues explore our understanding of the mechanisms of antibiotic resistance, including reduced permeability, antibiotic efflux, modification or alteration of the antibiotic target, modification or destruction of the drug itself, and bypass of metabolic pathways. They also discuss how this information can aid in developing the next generation of antimicrobial therapies.

    • Elizabeth M. Darby
    • Eleftheria Trampari
    • Jessica M. A. Blair
    Review Article
  • Soil viruses are highly abundant and have important roles in the regulation of host dynamics and soil ecology. In this Review, Jansson and Wu explore our current understanding of soil viral diversity and ecology, and how climate change (such as extended and extreme drought events or more flooding and altered precipitation patterns) is influencing soil viruses.

    • Janet K. Jansson
    • Ruonan Wu

    Collections:

    Review Article
  • This Review discusses the ecophysiology and diversity of Trichoderma and the complexity of its relationships in the agroecosystem environment. Considerations are also presented on how to advance Trichoderma applications in real-world scenarios, contributing towards eco-sustainable agriculture.

    • Sheridan L. Woo
    • Rosa Hermosa
    • Enrique Monte
    Review Article
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