News & Comment

Two new studies provide insights into the close association betweenWolbachiaspp. and their hosts; one shows plant-mediated transmission and the other the bacterial origin of a new host sex chromosome.

This study shows that circadian changes in the gut microbiota influence host physiology in the intestine and the liver.

This study shows that histones are loaded onto unintegrated Moloney murine leukemia virus DNAs shortly after they have entered the nucleus.

This study identifies 1,445 RNA viruses in invertebrate animals, including new virus families, and uncovers unexpected levels of evolutionary flexibility.

This study finds that quorum sensing, which is induced at high cell density, activates CRISPR–Cas immunity inPseudomonas aeruginosa.

Two studies discover new avenues that could be explored for the novel therapeutic intervention of fungal infections.

This study shows that the bacterial effector Sca4 promotes intercellular spread of the obligate intracellular pathogenRickettsia parkeriby disrupting the transmission of intercellular tension at cell–cell adherence junctions.

Three new studies investigate the metabolic pathways that anaerobic archaea use to produce hydrocarbons such as methane and butane.

This study reveals that ribosomal antibiotics function in a context-specific manner, dependent on the penultimate amino acid in the nascent chain and the amino acid in the P-site of the peptidyl transferase center.

This study reports that the T7SS has antibacterial activity and is involved in intraspecies competition.

This study reveals that arginine phosphorylation tags proteins for degradation by the ClpCP protease

This study reveals that TcdB binds to two different receptors, CSPG4 and FZD, in a cell type-dependent manner.

ProQ is revealed to be a global post-transcriptional regulator that stabilizes structured RNAs.

This study shows that T6SS components that are transferred between cells can be reused to assemble a fucntional T6SS system in the recipient.

Visualization of the morphogenesis and egress of a prototypical archaeal virus reveals some key similarities with eukaryotic viruses.

This study investigated the role of IFITM proteins in the restriction of HIV-1 strains that have different receptor tropism and identified IFITM proteins as major effectors of the innate immune response.

An RNA virus that infects mosquitoes is the first example of an animal virus with a multicomponent composition.

Two new studies investigate cell division in the human pathogensChlamydia trachomatis and Borreliaspp.

This study reports that the DENV non-structural protein NS4B induces elongation of mitochondria, and that this is linked to the formation of convoluted membranes, enhanced viral replication and impaired immune responses.

This study shows that dynamic pores in the capsid of HIV allow the import of substrates for reverse transcription, thereby shielding the reaction from the host cytosol.