News & Comment

This Comment article highlights the progress that has been made over the past 40 years since the discovery of HIV, and discusses the commitment needed to end the HIV/AIDS epidemic and the ongoing challenges.

This study shows how the bacterium Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice.

This Genome Watch highlights different tools and strategies used to enhance the quality of metagenome-assembled genomes (MAGs) generated in microbiome studies.

In this Journal Club, Gonzalo Moratorio discusses a study using deep mutational scanning (DMS) to uncover how the influenza virus evades the host immune response, highlighting the potential of DMS in understanding the evolutionary arms race between pathogens and hosts.

In this Journal Club, Anja Spang discusses the discovery of nanosized archaea, transforming our knowledge of archaeal phylogeny and shedding light on their roles in ecology and evolution.

In this Journal Club, Chelsey Spriggs discusses how the study of simian virus 40 (SV40) revealed a key sequence in the large T antigen that directs its transport into the cell nucleus, advancing our understanding of nuclear import mechanics.

In this Journal Club, Edmund Loh explores the pioneering work of Jun-Ichi Tomizawa and colleagues, which uncovers the importance of a small RNA in plasmid replication and elucidates its mechanism of action.

Marking 20 years of Nature Reviews Microbiology, we reflect on the increasing importance of microbiology in our ever-changing world.

In this Journal Club, Lisa Maier explores Abigail Salyers’ groundbreaking research on Bacteroides thetaiotaomicron, focusing on how she established a new genetic system and investigated how these gut bacteria bind and use starch, uncovering important insights into their metabolism.

In this Journal Club, Rebecca Shapiro discusses the discovery of the earliest antifungal drug, nystatin, by pioneering women Elizabeth Hazen and Rachel Brown.

In this Journal Club, Thulani Makhalanyane discusses research revealing the existence of diverse and novel defence islands in bacteria and archaea.

In this Journal Club, Tao Zuo discusses a study by Gogokhia et al. who found that gut bacteriophages can alter mucosal immunity to impact mammalian health.

In this Journal Club, Sarah Auburn discusses the pioneering development of the first framework for whole-genome sequencing of natural malaria infections, revolutionizing malaria genomics.

In this study, Prasad et al. show that Alcanivorax borkumensis optimizes oil consumption via formation of tubular biofilms.

This study shows that intercellular long extensions promote the evasion of antibody neutralization and the efficient intercellular transmission of chikungunya virus in vitro and in vivo.

This month’s Genome Watch highlights the use of high-depth genome-centric approaches to further our understanding of the human gut microbiome within the context of industrialized and non-industrialized lifestyles.

This study shows that a gut peptide is active against virulent forms of Candida albicans, thus contributing to the maintenance of fungal commensalism.

This Genome Watch highlights how the integration of genomic surveillance with epidemiological or clinical data can help understand pathogen transmission and improve public health interventions for infectious disease control.

In this study, Huang et al. discover Delftia tsuruhatensis TC1, a mosquito symbiotic bacterium that inhibits parasite development via the secretion of a small molecule.

In this study, Sharafutdinov et al. report a single nucleotide polymorphism in the gene encoding the HtrA protease of Helicobacter pylori that is associated with gastric cancer.