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  • This study reports that intracellular cord formation by Mycobacterium tuberculosis is an important feature of early pathogenesis.

    • Andrea Du Toit
    Research Highlight
  • In this study, Yan et al. developed a broad-spectrum protein-free vaccine that protects against infection with bacterial and fungal nosocomial pathogens.

    • Agustina Taglialegna
    Research Highlight
  • This study reports the identification of the novel Candida auris-specific adhesin Scf1, which, together with the adhesin Iff4109, is a key mediator of surface association, infection and long-term colonization.

    • Andrea Du Toit
    Research Highlight
  • This study found that the bacterial second messenger cyclic diguanylate (c-di-GMP) has a key role in establishing host–bacteria symbiosis.

    • Ashley York
    Research Highlight
  • This Comment article highlights the progress that has been made over the past 40 years since the discovery of HIV, and discusses the commitment needed to end the HIV/AIDS epidemic and the ongoing challenges.

    • Linda-Gail Bekker
    Comment
  • This Genome Watch highlights different tools and strategies used to enhance the quality of metagenome-assembled genomes (MAGs) generated in microbiome studies.

    • Rex R. Malmstrom
    Genome Watch
  • In this Journal Club, Gonzalo Moratorio discusses a study using deep mutational scanning (DMS) to uncover how the influenza virus evades the host immune response, highlighting the potential of DMS in understanding the evolutionary arms race between pathogens and hosts.

    • Gonzalo Moratorio
    Journal Club
  • In this Journal Club, Anja Spang discusses the discovery of nanosized archaea, transforming our knowledge of archaeal phylogeny and shedding light on their roles in ecology and evolution.

    • Anja Spang
    Journal Club
  • In this Journal Club, Chelsey Spriggs discusses how the study of simian virus 40 (SV40) revealed a key sequence in the large T antigen that directs its transport into the cell nucleus, advancing our understanding of nuclear import mechanics.

    • Chelsey C. Spriggs
    Journal Club
  • In this Journal Club, Edmund Loh explores the pioneering work of Jun-Ichi Tomizawa and colleagues, which uncovers the importance of a small RNA in plasmid replication and elucidates its mechanism of action.

    • Edmund Loh
    Journal Club
  • In this Journal Club, Lisa Maier explores Abigail Salyers’ groundbreaking research on Bacteroides thetaiotaomicron, focusing on how she established a new genetic system and investigated how these gut bacteria bind and use starch, uncovering important insights into their metabolism.

    • Lisa Maier
    Journal Club
  • In this Journal Club, Rebecca Shapiro discusses the discovery of the earliest antifungal drug, nystatin, by pioneering women Elizabeth Hazen and Rachel Brown.

    • Rebecca S. Shapiro
    Journal Club
  • In this Journal Club, Tao Zuo discusses a study by Gogokhia et al. who found that gut bacteriophages can alter mucosal immunity to impact mammalian health.

    • Tao Zuo
    Journal Club