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This Genome Watch highlights the advances made in bacterial single-cell RNA sequencing, specifically in the context of host–microorganism interaction studies.
In this Review, Holmes and colleagues explore the mechanisms by which healthcare functions as a driver, reservoir and amplifier of antimicrobial resistance (AMR), and they explore opportunities and innovative solutions to mitigate healthcare-associated AMR and promote healthcare resilience.
In this Review, Kunath et al. explore the interaction between the oral and the intestinal microbiota and how they influence each other and the development of different diseases.
In this Review, Gilbert and Hartmann examine the microbial ecology of indoor spaces, the factors that influence the microbiome of the built environment, and their influence on human health.
In this Review, Duffy et al. examine the malaria vaccine landscape, showcasing both achievements and setbacks over the past decades. They discuss approaches and assays for different parasite stages, summarize recent advancements, propose a decision-making process for the field and identify future priorities to address unmet needs.
Most plants form symbioses with arbuscular mycorrhizal fungi, which themselves harbour endobacteria and hyphospheric bacteria. In this Review, Duan et al. explore how nutrients are transferred between the partners in this plant–fungus–bacterium continuum.
In this Review, Stanton and colleagues examine the effect of different whole diets on the composition and function of the gut microbiome and explore how the diet–microbiome relationship influences human health and the progression of different chronic diseases.
A WHO report suggests the terms ‘airborne transmission/inhalation’, ‘direct deposition’ and ‘infectious respiratory particles’ for describing transmission modes, highlighting the continuum of particle size with greatest exposure near the source. The report did not update infection control guidelines.
This month’s Genome Watch highlights the use of genetic barcoding towards a better understanding of plant–microorganism interactions and colonization dynamics.
In this Review, Brown et al. provide an overview of fungal pathobiology from the pathogen, host and clinical perspectives, focusing specifically on pathogens that can cause invasive life-threatening infections.
In this Review, Domenech de Cellès and Rohani explore the contemporary epidemiology of pertussis and discuss the controversies surrounding the mechanisms responsible for the re-emergence of pertussis, including the effectiveness and duration of natural immunity and vaccine-derived immunity, the ability of vaccines to prevent transmission and severe disease, and the impact of evolution on evading vaccine immunity.
This Review explores recent insights into the evolutionary history, the environmental adaptation and the colonization and dissemination mechanisms of Enterococcus faecium, and highlight potential novel preventative and therapeutic approaches to its infections.