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An imaging technique can acquire surface-enhanced Raman scattering intensity fluctuations at 800,000 frames per second, revealing the dynamics of plasmonic hotspots at the single-particle level.
Catalytic gold nanoclusters that respond to protease activity in vivo and are excreted in urine can offer a quick colorimetric tool for disease detection in resource-limited settings.
Local changes of the Coulomb interaction due to external dielectric environment fluctuations present a new type of disorder in monolayer transition-metal dichalcogenides.
Automated 3D design produces rapid and near-atomically accurate predictions of RNA tertiary structure as well as the ability to generate complex RNA machines such as functional single-stranded tethered ribosomes, and enhancement of the binding properties of small-molecule RNA aptamers.
A repeated on–off high-temperature shockwave is shown to be a generalizable way of efficiently synthesizing and stabilizing single atoms at high temperatures.
Subject to force, molecules are more likely to move down a step defect than up the defect and are even more likely to be displaced along the step defect line.
Combination of dendritic-cell-targeted nanovaccines with a myeloid-derived suppressor cell inhibitor and immune checkpoint modulators expands the host antitumour immune cells, restricts tumour growth and prolongs survival in orthotopic melanoma models.
An in situ only fabrication process for networks of topological insulator–superconductor Josephson junctions with high interface transparency is introduced, which holds some potential for the production of future topological quantum computing networks.
Glutathione-mediated biotransformation in the liver sinusoids could modulate nanoparticle transport in vivo, which can be exploited to design nanoparticles with enhanced tumour targeting and reduced non-specific accumulation in the body.
An optoelectronic resistive switching memory synaptic device enables the realization of an efficient neuromorphic visual system exhibiting non-volatile optical resistive switching and light-tunable synaptic behaviours.
Nanopore AFM is used for the stochastic sensing of secreted molecules and the activity of ion channels in arbitrary locations both inside and outside a cell.
The combination of two-photon lithography and high-temperature pyrolysis is used to create micro-sized pyrolytic carbon with a compressive strength of 9.79 GPa cm3 g−1. This enables rubber-like behaviour in micropillars, which can sustain compressive strain up to 50%.
Scalable ultrasmall U-shaped nanowire FET probe arrays enable recording of full amplitude intracellular action potentials from primary neurons and other electrogenic cells.
A zwitterionic camptothecin–polymer conjugate that is enzymatically transformed in a cationic molecule at the tumour periphery penetrates deep into tumours via caveolae-mediated endocytosis and transcytosis, resulting in high anticancer efficiency in vivo.
In a breast cancer animal model, long-term exposure to carbon nanotubes promotes tumour invasiveness and metastasis through activation of local and systemic inflammation.
A nanoporous polyimide film filled with a solid polymer electrolyte has high ionic conductivity and high mechanical strength. An all-solid-state battery made with an approximately 10-μm-thick film shows good cyclability at 60 °C and no dendrite formation.