News & Comment

Treatment with REGEN-COV helps to prevent COVID-19 in household contacts of infected people, according to a phase 3 trial.

Myriad genetic and biological factors control the timing of menopause—understanding these has implications for fertility and health.

Researchers sift through the experiences of transgender and nonbinary youths to define barriers to healthcare access and drivers of positive outcomes.

A large-scale genetic sequencing study reveals a potential new therapeutic target in obesity.

Drinking patterns contribute substantially to cancer incidence, according to a global population-based study.

Gefitinib with lenvatinib shows promising antitumor activity in patients whose cancers had progressed on lenvatinib monotherapy.

Occipital nerve stimulation reduced the frequency of attacks in patients with uncontrolled chronic cluster headaches.

Two large studies report positive data for CoronaVac in both clinical-trial and real-world settings.

Integrating CRISPR technology into a wearable mask enables rapid and accurate detection of SARS-CoV-2.

A study in mice shows how novel mRNA vaccine designs could provide protection against multiple coronaviruses in a single formulation.

For patients with early-stage breast cancer and a high risk of recurrence, addition of the PARP inhibitor olaparib to standard treatments reduced the risk of the cancer returning.

Myeloid cells and B cells that patrol the brain and spinal cord originate in the skull and vertebral bone marrow, and are distinct from their blood-derived counterparts.

A ‘swarm learning’ technique enables AI-based diagnosis with enhanced data security and confidentiality.

A lentivirus-based treatment restores immune function with minimal side effects in children with adenosine deaminase deficiency.

Critically ill patients with COVID-19 in Africa are at higher risk of death than those elsewhere.

Two studies report that antiseptic mouthwash does not reduce the incidence of oral sexually transmitted infections.

A brain implant in a paralyzed person can decode neuronal activity into accurate text communication.

An oral antisense oligonucleotide that targets PCSK9 was shown to reduce LDL cholesterol in animal models, supporting further clinical development.

The RECOVERY study shows that anti-IL-6 agent tocilizumab improves outcomes in hypoxic patients with COVID-19.

Stimulants and α₂-adrenergic agonists both improve symptoms of ADHD in preschool-age children, but they have different side effects.