Langerhans cells in the skin and mucosa have been thought to mediate the spread of HIV-1 in the body during sexual transmission. Instead, it seems that the cells protect against the virus, a finding with implications for the development of microbicides (pages 367–371).
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References
Jolles, S. J. Clin. Pathol. 55, 243 (2002).
de Witte, L. et al. Nat. Med. 13, 367–371 (2007).
Kissenpfennig, A. & Malissen, B. Trends Immunol. 27, 132–139 (2006).
Valladeau, J., Dezutter-Dambuyant, C. & Saeland, S. Immunol. Res. 28, 93–107 (2003).
Valladeau, J. et al. Immunity 12, 71–81 (2000).
Verdijk, P. et al. J. Invest. Dermatol. 124, 714–717 (2005).
Turville, S.G. et al. Nat. Immunol. 3, 975–983 (2002).
Kawamura, T., Kurtz, S.E., Blauvelt, A. & Shimada, S. J. Dermatol. Sci. 40, 147–155 (2005).
Moris, A. et al. Blood 108, 1643–1651 (2006).
Klasse, P.J., Shattock, R.J. & Moore, J.P. PLoS Med. 3, e351 (2006).
Hu, J., Gardner, M.B. & Miller, C.J. J. Virol. 74, 6087–6095 (2000).
Auvert, B. et al. PLoS Med. 2, e298 (2005).
Hladik, F. et al. Immunity, published online 12 February 2007 (doi: 10.1016/j.immuni.2007.01.007)
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Schwartz, O. Langerhans cells lap up HIV-1. Nat Med 13, 245–246 (2007). https://doi.org/10.1038/nm0307-245
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DOI: https://doi.org/10.1038/nm0307-245