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In newborn infants, permanent closure of a major blood vessel connecting the main pulmonary artery to the aorta is essential to allow adequate circulation of blood to major organs. Platelet aggregation now emerges as a crucial step in this process in newborn mice and, possibly, in preterm infants (pages 75–82).
Tumors use many strategies to evade the immune system. A new study adds a new trick to the list—inhibiting the migration of dendritic cells from tumors toward lymph nodes (pages 98–105).