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Tuft cells in the intestine, immunity and beyond
Tuft cells have important roles in type 2 immunity and antimicrobial responses in mucosal tissues. This Review provides an overview of intestinal tuft cells, providing insights into their phenotype, function and role in the intestine in immunity and other states.
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MASLD/NAFLD
Fuelled by increasing obesity rates, metabolic dysfunction associated steatotic liver disease (MASLD, formerly known as NAFLD) has emerged as a leading global cause of chronic liver disease in the past few decades. Despite growing prevalence, the factors influencing MASLD development and subsequent progression to metabolic dysfunction associated steatohepatitis (MASH), liver fibrosis, cirrhosis and hepatocellular carcinoma are poorly understood. In this article series, Nature Reviews Gastroenterology & Hepatology explores the epidemiology of MASLD, disease mechanisms and therapeutics, and clinical approaches to diagnosis and management.
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Therapeutic landscape and future direction of metastatic colorectal cancer
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Noninvasive imaging biomarker assessment of liver fibrosis by elastography in NAFLD
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Oropharyngeal dysphagia: manifestations and diagnosis
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Strengthening the foundation of African microbiome research: strategies for standardized data collection