Antibiotics promote the spread of resistance in the clinic, but various mechanisms may exist in natural environments that tilt the balance toward antibiotic sensitivity. Studying such mechanisms could help us understand the evolutionary dynamics of resistance and sensitivity in the wild, which may inspire new therapeutic strategies.
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Chait, R., Vetsigian, K. & Kishony, R. What counters antibiotic resistance in nature?. Nat Chem Biol 8, 2–5 (2012). https://doi.org/10.1038/nchembio.745
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DOI: https://doi.org/10.1038/nchembio.745
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