Bacterial pathogen–secreted proteases may have a key role in inhibiting a potentially widespread host-pathogen interaction. Activity-based protein profiling enabled the identification of a major Vibrio cholerae serine protease that limits the ability of a host-derived intestinal lectin to bind to the bacterial pathogen in vivo.
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Wright, A. A cholera surveillance system. Nat Chem Biol 12, 203–204 (2016). https://doi.org/10.1038/nchembio.2039
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DOI: https://doi.org/10.1038/nchembio.2039