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Using a BioID approach, Bagci et al. systematically analyse the Rho-family GTPase interactome and reveal previously unappreciated interactions with RhoGEFs and RhoGAPs and effectors for Rho proteins.
Brumbaugh, Kim et al. generate mice with inducible H3 K-to-M mutations, which globally inhibit methylation at specific sites, and analyse specific phenotypes and changes in chromatin accessibility and transcriptional programmes.