Volume 19 Issue 9, September 2001

The cover shows herpes simplex virus (shown here magnified 150,000 times using a transmission electron microscope), which has been detected using an antibody-coated quartz crystal microbalance described by Klenerman and colleagues on p. 833. The trace at the bottom represents the acoustic signal observed upon detachment of a single virion from the quartz crystal using rupture event scanning (REVS). Virus image by Alfred Pasieka/Science Photo Library.

Editorial

The politics of principles

Editorial 01 Sept 2001

Advertisement

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Business and Regulatory News

US deliberates on embryonic stem cells, cloning

Jeffrey L. Fox
Business and Regulatory News 01 Sept 2001
New Zealand backs GM technologies

Cheryl Norrie
Business and Regulatory News 01 Sept 2001
US rejects stronger bioweapons treaty

Emma Dorey
Business and Regulatory News 01 Sept 2001
IT giants muscle into life science arena

Liz Fletcher
Business and Regulatory News 01 Sept 2001
EU plans to label and trace GMOs

Emma Dorey
Business and Regulatory News 01 Sept 2001
Racially defined haplotype project debated

Debra Robertson
Business and Regulatory News 01 Sept 2001
GM crops are no panacea for poverty

Liz Fletcher
Business and Regulatory News 01 Sept 2001
Quicker drug approvals on the way for Europe

Sylvia Davidson
Business and Regulatory News 01 Sept 2001
In Brief

Business and Regulatory News 01 Sept 2001

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Commentary

The protein trinity—linking function and disorder

A. Keith Dunker
Zoran Obradovic
Commentary 01 Sept 2001
The Bush administration deals a blow to biotechnology—and itself

Henry I. Miller
Commentary 01 Sept 2001

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Book Review

Separating fact from fiction science

Terry Gaasterland
Kass Schmitt
Book Review 01 Sept 2001

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Correspondence

Too much of a good thing?

Mark Burkitt
Correspondence 01 Sept 2001
In defense of the precautionary principle

Carolyn Raffensperger
Katherine Barrett
Correspondence 01 Sept 2001
Estrogenic impurities in labware

Toshio Ishikawa
Koji Takano
Keishi Hata
Correspondence 01 Sept 2001

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Feature

Putting a price on biotechnology

Many bioentrepreneurs incorrectly estimate the value of their technology by failing to account adequately for the cost, risk, and time inherent in product development.

Jeffrey J. Stewart
Peter N. Allison
Ronald S. Johnson
Feature 01 Sept 2001
Monoclonal antibodies in the clinic

Despite initial teething problems, the number of clinically effective monoclonal antibodies is growing.

Janice M. Reichert
Feature 01 Sept 2001

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News & Views

Listening for viral infection

Biosensors based on a quartz crystal microbalance show promise for sensitive and rapid viral detection.

Erica Ollmann Saphire
Paul W.H.I. Parren
News & Views 01 Sept 2001
Genetic selection and the lure of SIN

A rapid method for exploring gene function uses alphavirus expression cloning.

Garry P. Nolan
News & Views 01 Sept 2001
Plastid engineering bears fruit

The tomato has been engineered to express in its plastids high levels of a recombinant protein.

Pal Maliga
News & Views 01 Sept 2001
Proteomics comes to the surface

Microarrays of purified proteins, representing most of the yeast genome, prove useful for studying protein function on a genome-wide scale.

Gavin MacBeath
News & Views 01 Sept 2001

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News in Brief

In Brief

News in Brief 01 Sept 2001

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Article

Direct and sensitive detection of a human virus by rupture event scanning

Matthew A. Cooper
Fedor N. Dultsev
David Klenerman
Article 01 Sept 2001
Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

Paul N. Reynolds
Stuart A. Nicklin
David T. Curiel
Article 01 Sept 2001
High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain

H. Michael Keyoung
Neeta S. Roy
Steven A. Goldman
Article 01 Sept 2001
A high-throughput alphavirus-based expression cloning system for mammalian cells

Daniel Koller
Christiane Ruedl
Martin F. Bachmann
Article 01 Sept 2001
Bioassay of prostate-specific antigen (PSA) using microcantilevers

Guanghua Wu
Ram H. Datar
Arun Majumdar
Article 01 Sept 2001
Single-molecule observation of protein–protein interactions in the chaperonin system

Hideki Taguchi
Taro Ueno
Takashi Funatsu
Article 01 Sept 2001
Affinity capture of proteins from solution and their dissociation by contact printing

André Bernard
Dora Fitzli
Hans Biebuyck
Article 01 Sept 2001
Stable genetic transformation of tomato plastids and expression of a foreign protein in fruit

Stephanie Ruf
Marita Hermann
Ralph Bock
Article 01 Sept 2001

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Technical Report

Genotyping of dinucleotide tandem repeats by MALDI mass spectrometry of ribozyme-cleaved RNA transcripts

Stefan Krebs
Doris Seichter
Martin Förster
Technical Report 01 Sept 2001

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Patents

Going for the big one

Ronald I. Eisenstein
David S. Resnick
Patents 01 Sept 2001
Recent patents in bioinformatics

Patents 01 Sept 2001

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People

People

People 01 Sept 2001

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New on the Market

Microarrays and centrifugation

New on the Market 01 Sept 2001

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Careers and Recruitment

Finance offers intellectual challenges and economic rewards

More and more scientists are finding stimulation, fulfillment, and pecuniary rewards in the financial sector.

Paul Smaglik
Careers and Recruitment 01 Sept 2001

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Volume 19 Issue 9, September 2001

Editorial

Business and Regulatory News

Commentary

Book Review

Correspondence

Feature

News & Views

News in Brief

Article

Technical Report

Patents

People

New on the Market

Careers and Recruitment

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