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Nematode bacterial symbionts were evolved in vitro to resist insect-sequestered plant toxins to improve the insect-killing efficacy of their nematode host.
Methods to efficiently detect Cas9-independent cytosine base editor off-target activity enable the identification and development of variants with minimal off-target editing and robust on-target editing.
Combining single-cell RNA-seq data and microarray-based spatial transcriptomics maps the location of different cell types and cell states in pancreatic tumors.