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Drug hunters are finding that ancient virus-like artifacts in the human genome could offer new avenues to treat neurodegeneration, cancer, autoimmunity and even aging with antibodies, vaccines and antiretroviral agents.
Borderlands Science is a casual mini-game released within a mass-market video game that crowdsources the alignment of one million RNA sequences from the human microbiome. In 3 years, 4 million participants generated over 135 million puzzle solutions that were used to build a reference alignment and improve microbial phylogeny.
A pioneer in the emerging fields of AI for antibiotic discovery and molecular de-extinction describes his transdisciplinary background and lifelong passion to understand biology.
Although the clinical application of induced pluripotent stem cells is still in its infancy, the development of iPSC technologies reflected by an increasing number of patents provides hope that they will realize their therapeutic potential.
Longitudinal evaluation of the Biomedical Entrepreneurship Educational Program suggests the program successfully educates and inspires the next generation of life science and biotechnology innovators.
Using synthetic biology, we engineered a cellulose-producing bacterium that can produce eumelanin and respond to light, so that it is possible to grow a microbial leather material that is colored black or contains projected black patterns.
Cells interact with their local environment to enact global tissue function. By harnessing gene–gene covariation in cellular neighborhoods from spatial transcriptomics data, the covariance environment (COVET) niche representation and the environmental variational inference (ENVI) data integration method model phenotype–microenvironment interplay and reconstruct the spatial context of dissociated single-cell RNA sequencing datasets.
Using gene–gene covariance structure to represent cellular neighborhoods improves the integration of single-cell RNA sequencing and spatial transcriptomics data.
VitaDAO funds longevity research through a blockchain-based decentralized autonomous organization (DAO), showcasing the potential of collaborative, transparent and alternative systems while also highlighting the challenges of coordination, regulation, biases and skepticism in reshaping traditional research financing methods.