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Volume 403 Issue 6770, 10 February 2000

Opinion

  • Clinton's belated decision to invest heavily in basic science and engineering at the National Science Foundation deserves to win the support of his political opponents on Capitol Hill.

    Opinion

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  • Renewed interest in a scientific approach to global problems is welcome, but needs sensitive treatment.

    Opinion
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News

  • Munich

    The European Laboratory for Particle Physics (CERN) is planning to announce today (10 February) that it has “compelling evidence” that it has successfully created the quark–gluon state of matter predicted to have existed shortly after the Big Bang.

    • Alison Abbott
    News
  • Washington

    Guidelines issued recently by the US National Institutes of Health limiting restrictions on the use of research tools have come under fire from representatives of several small biotech companies at a symposium on intellectual property.

    • Paul Smaglik
    News
  • Washington

    Dan Goldin, administrator of the US space agency NASA, has ordered a sweeping review of all spacecraft missions scheduled for launch in the coming year following a spate of high-profile failures.

    • Tony Reichhardt
    News
  • Washington

    Legislation altering the oversight of all federally funded human clinical gene therapy trials was introduced into the US House of Representatives last week.

    • Paul Smaglik
    News
  • Munich

    German genome scientists and industrial research managers have rejected accusations by a top government official that they have not been doing enough to convince the government of the political importance of genome research.

    • Alison Abbott
    News
  • Washington

    President Bill Clinton's eighth and last budget proposal — submitted to Congress on Monday — would give several US science agencies a larger increase than any of his previous budgets.

    • Colin Macilwain
    • Tony Reichhardt
    • Paul Smaglik
    News
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News Profile

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News in Brief

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Correspondence

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Book Review

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Millennium Essay

  • Every living thing obeys the rules of scaling discovered by Max Kleiber.

    • Vaclav Smil
    Millennium Essay
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Futures

  • An elegant demonstration that the Universe is made of quantum graphs.

    • Greg Egan
    Futures
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News & Views

  • Clues to the function of a protein can be obtained by seeing whether it interacts with another protein of known function. This principle of guilt-by-association has now been applied to the entire protein complement of yeast.

    • Stephen Oliver
    News & Views
  • Jupiter's atmosphere is famous for its storm systems, such as the Great Red Spot, which has been active for more than 300 years. What drives Jupiter's turbulent weather has long been a matter of debate. New images from the Galileo spacecraft indicate that moist convection — familiar from thunderstorms on Earth — transports energy upwards through the clouds.

    • Alvin Seiff
    News & Views
  • When people are deprived of sleep their performance in various tasks is impaired. But the degree of impairment depends on the nature of the test — for example, the effects of sleep deprivation are far more likely to be felt if the test is boring. Assessment of performance has mainly been subjective, but one group has now examined the effects of sleep deprivation using brain-imaging techniques.

    • Jim Horne
    News & Views
  • Creating new enzymes by ‘rational design’ has proved to be extremely difficult. A new approach combines structural modification with natural selection — so-called ‘directed evolution’. With this technique, one enzyme in a biosynthetic pathway can be converted into another enzyme with a completely different function.

    • Gregory A. Petsko
    News & Views
  • The Hox gene family contains 39 related genes that are crucial for development in mammals. By swapping the protein-coding regions of Hox genes around, it has been shown that the function of a Hox gene may depend not on which protein it produces, but on where, when and how strongly it is expressed.

    • Denis Duboule
    News & Views
  • The possibility that there are regions in the Universe where time runs in the opposite direction to ours seems bizarre. But taken seriously, this idea may reveal something about the nature of dark matter.

    • Peter T. Landsberg
    • James Vickers
    News & Views
  • Lake Vostok is a giant, freshwater lake hidden below the East Antarctic ice sheet. There is some evidence that the lake may contain ancient life. Radar data now confirms that ice melts and refreezes at the base of the ice sheet in a way that encourages circulation of the water. This has implications for the survival of life in the lake.

    • Charles R. Bentley
    News & Views
  • Houses have roofs and foundations which are built of different materials and require upkeep. Likewise, cells — especially for instance those that form an epithelial sheet — have a top and bottom, and the right proteins have to be directed to the right place throughout the cells' lives. A molecule called Scribble now emerges as a central player in the maintenance of cell polarity in the fruitflyDrosophila.

    • Mark Peifer
    • Ulrich Tepass
    News & Views
  • Blood clotting in the wrong place in the human body can be a killer. Daedalus plans to tackle the problem with an innovative use of ultrasound. A converging beam directed for a time to, say, one of the wider arteries, will agitate the blood, break up any incipient clots and keep blood safely fluid.

    • David Jones
    News & Views
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Brief Communication

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Article

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Letter

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New on the Market

  • This week's offerings include the “smallest IR camera in the world”.

    New on the Market
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