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If the threat of global warming is serious (which cannot be denied), it deserves more seemly ways of making authoritative opinion public than that followed at last week's meeting at Maastricht.
WD proteins are made up of highly conserved repeating units usually ending with Trp-Asp (WD). They are found in all eukaryotes but not in prokaryotes. They regulate cellular functions, such as cell division, cell-fate determination, gene transcription, transmembrane signalling, mRNA modification and vesicle fusion. Here we define the common features of the repeating units, and criteria for grouping such proteins into functional subfamilies.
Research tools for the immunologist include a new class of mitochondrion-selective fluorescent dyes, ELISAs for urokinase-type plasminogen activator and cathepsin D and a host of antibodies and reagents.
