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Most governments have reacted somehow to the AIDS epidemic, some regrettably illiberally but none has given epidemiology its due, in particular its capacity to rid us of uncertainties.
A French company's understandable pride in having built a conspicuous structure in Paris nearly a century ago may persuade it to ruin optical astronomy for several years to come.
Simple mathematical models of the transmission dynamics of human immunodeficiency virus help to clarify some of the essential relations between epidemiological factors, such as distributed incubation periods and heterogeneity in sexual activity, and the overall pattern of the AIDS epidemic. They also help to identify what kinds of epidemiological data are needed to make predictions of future trends.
The complementary DNA sequence encoding the Mr 28,000 antigen of Schistosoma mansoni has been isolated and expressed in Escherichia coli. Experimental vaccination of rats, hamsters and monkeys with a recombinant fusion protein induces a strongly cytotoxic antibody response. Immunization of rats and hamsters with this protein leads to significant protection against a natural challenge infection with live cercariae.
The primary structures of four bovine clathrin light chains have been determined. Light chains LCa and LCb are homologous proteins encoded by different genes. In the brain the messenger RNA from these genes undergoes differential splicing to yield proteins having centrally inserted brain-specific sequences. A potentially α-helical region of the clathrin light chains shows homology with intermediate filament proteins.
Publishers are not serving some of their authors or student customers as well as they might. Wallace S. Broecker describes his experience of desk-top publishing, and suggests how authors could make themselves a force to contend with.
