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Observation of a many-body pairing gap in a trapped, 2D atomic Fermi gas shows that ultracold atomic gases can be used to emulate the physics of correlated 2D superconductors, with the ultimate goal of understanding high-temperature superconductivity.
Earth's mantle is likely to have reached its present-day oxidation state before 4 billion years ago, according to a determination of the oxidation state of Hadean magmatic melts.
An atomic analogue to homodyne detection for the measurement of matter-wave quadratures is realized, which is needed to extend quantum applications to massive particles.
Genome-wide analysis shows that H2B S112 O-linked to N-acetylglucosamine is frequently located near transcribed genes, suggesting that histone GlcNAcylation facilitates transcription of the genes.
Thymus-derived regulatory T cells are activated by recognition of peripheral self antigen, persist in the target tissue on cessation of antigen exposure, and respond to re-exposure to self antigen with enhanced functional activity.
Crystallographic studies show that high-molecular-mass drugs bind to the bacterial multidrug transporter AcrB at a previously unseen ‘proximal’ binding pocket before peristaltic transfer to the known ‘distal’ pocket, whereas low-molecular-mass drugs bind directly to the distal pocket.
The NMR structure of the murine leukaemia virus recoding translational signal is determined, giving insight into the mechanism of read-through in retroviruses.
The crystal structure of the enzyme MCR from methanogenic archaea shows that it is very similar to that of methanotrophic archaea; the differences observed may tune the enzymes for their respective biological context within the sea mats.
Piwi protein Miwi is shown to be a small RNA-guided RNase in mice; disrupting the catalytic activity of Miwi results in increased accumulation of LINE1 retrotransposon transcripts and male infertility.
Although clinical trials have shown that RAF inhibitors prolong the survival of patients with BRAF-mutant melanoma, resistance inevitably develops; resistance is shown here to be frequently mediated by the expression of splicing variants of mutant BRAF.