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Cancer

Crossing over to drug resistance

Certain cancers stem from mutations that prevent a cell from repairing its damaged DNA efficiently. But antitumour chemotherapy that exploits that repair defect can in turn be nullified by counter-mutation.

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References

  1. Edwards, S. L. et al. Nature 451, 1111–1115 (2008).

    Article  CAS  ADS  Google Scholar 

  2. Sakai, W. et al. Nature 451, 1116–1120 (2008).

    Article  CAS  ADS  Google Scholar 

  3. Bryant, H. E. et al. Nature 434, 913–917 (2005).

    Article  CAS  ADS  Google Scholar 

  4. Farmer, H. et al. Nature 434, 917–921 (2005).

    Article  CAS  ADS  Google Scholar 

  5. Nagrath, S. et al. Nature 450, 1235–1239 (2007).

    Article  CAS  ADS  Google Scholar 

  6. Furuta, S. et al. Cancer Cell 10, 13–24 (2006).

    Article  CAS  Google Scholar 

  7. Kinzler, K. W. & Vogelstein, B. Nature 386, 761–763 (1997).

    Article  CAS  ADS  Google Scholar 

Download references

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Livingston, D., Silver, D. Crossing over to drug resistance. Nature 451, 1066–1067 (2008). https://doi.org/10.1038/4511066a

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