Perfusion chromatography is a technique based on fluid dynamics for reducing stagnant mobile phase mass transfer in liquid chromatography. This is achieved by using supports with large pores that allow mobile phase to flow through particles.
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Regnier, F. Perfusion chromatography. Nature 350, 634–635 (1991). https://doi.org/10.1038/350634a0
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DOI: https://doi.org/10.1038/350634a0