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A biocompatible probe that combines fluorescent nanodiamonds and gold nanoparticles allows cells to be imaged using both optical and electron microscopy techniques, opening up fresh opportunities for biological research.
Polymeric semiconductors have been prepared whose molecular properties make them stretchable and healable — a milestone in the development of sophisticated organic electronic surfaces that mimic human skin. See Letter p.411
Anaerobic microbes have been found to break down the hydrocarbon butane by a pathway with some similarities to anaerobic methane breakdown. Harnessing the butane pathway might enable biofuel generation. See Article p.396
Repair enzymes must communicate across hundreds of nucleotides to undo errors made during DNA replication. Imaging reveals that the enzymes do this by forming a series of ring-like clamps that diffuse along the DNA. See Letter p.583
Interactions between the magnetic dipoles of dysprosium atoms in an ultracold gas can produce a 'self-bound' droplet. This provides a useful isolated system for probing the quantum-mechanical properties of ultracold gases. See Letter p.259
Two monkeys subjected to a spinal-cord injury that paralysed one leg have regained the ability to walk, thanks to technology that re-establishes communication between the brain and spinal cord. See Letter p.284
A nanoscale imaging method that uses ultrashort light pulses to initiate and follow the motion of a single molecule adsorbed on a solid surface opens a window onto the physical and chemical dynamics of molecules on surfaces. See Letter p.263
Observations of a real-time invasion of Australia by Asian honeybees demonstrate how natural selection can allow a small founding population to overcome the genetic odds stacked against success.
Injured blood vessels are repaired by vascular smooth-muscle cells. It emerges that the protein Fat1 regulates the proliferation of these cells by inhibiting the function of mitochondria. See Letter p.575
In many mammals, the gene Ostn is expressed in muscles and bones. The discovery that the primate OSTN gene has been repurposed to also act in neurons provides clues to how humans evolved their cognitive abilities. See Article p.242
Random lasers use disordered structures to produce light, which is usually emitted in many directions. A random laser that can produce a collimated beam offers a wide range of applications, from imaging to security scanning.
The discovery of a cascade of sound waves across many wavelengths in an ultracold atomic gas advances our understanding of turbulence in fluids governed by quantum mechanics. See Letter p.72
Physicists are hunting for a particle called the axion that could solve two major puzzles in fundamental physics. An ambitious study calculates the expected mass of this particle, which might reshape the experimental searches. See Letter p.69 See Clarificationp.176
A previously unknown way in which cells mark proteins for destruction has been found in bacteria — phosphorylation of the amino acid arginine targets proteins for degradation by protease enzymes. See Article p.48
Sleep in mammals consists of non-rapid-eye-movement and rapid-eye-movement sleep. A large genetic screen reveals that these two sleep states are altered in mice by mutations dubbed Sleepy and Dreamless. See Article p.378
Binary and multiple star systems result from the fragmentation of dense material in young molecular clouds. Observations reveal that this can occur on small scales, supporting a previous model of star formation. See Letter p.483
Expression of a blood-cancer-associated genetic mutation in the non-blood cells of the bone marrow is sufficient to cause blood cancer in mice. This finding could point to new approaches to treating an often-fatal disease. See Letter p.304