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Topological nanoelectromechanical metamaterials are realized at the micrometre scale, using silicon nitride nanomembranes, opening the way for on-chip integrated acoustic components in high-frequency signal-processing applications.
Evaluation of the efficiency of land-use changes and their effect on global carbon storage shows that several land-use and consumption choices relevant to climate policy have greater implications than previously thought.
Atrial natriuretic peptide, an anti-inflammatory protein, can protect against cytokine release syndrome induced by therapeutic agents such as tumour-targeting bacteria and CAR-T cells by blocking catecholamine synthesis by macrophages.
In mouse macrophages, a range of short and non-ATG-initiated open reading frames that can generate proteins are identified, one of which is shown to be essential for host immunity to enteric mucosal infection and inflammation.
A method for encoding the non-canonical amino acid 2,3-diaminopropionate into proteins allows key acyl intermediates in the biosynthesis of valinomycin to be trapped, providing insight into the oligomerization and cyclization reactions involved.
Direct observation of incommensurate spin correlations in doped and spin-imbalanced Hubbard chains confirms two fundamental predictions for Luttinger liquids and shows that such correlations are suppressed by interchain coupling.
Misexpression of the sperm-cell-expressed transcription factor BABY BOOM1 in the rice egg cell induces embryo development without fertilization, establishing the feasibility of asexual reproduction in crops and potentially enabling the clonal propagation of hybrids through seeds.
An electrically controlled phase transition from topological insulator to conventional insulator in ultrathin films of the topological Dirac semimetal, Na3Bi.
In mice, the ablation of spinal neurons that co-express TAC1 and LBX1 leads to the loss of coping responses to sustained pain without affecting reflexive defensive reactions to external threats.
SETD3 methylates mammalian actin at His73, and SETD3 deficiency impairs stimulus-induced contraction in primary human uterine smooth muscle cells and leads to maternal dystocia in mice.
Satellite observations reveal over 200 ammonia hotspots associated with agricultural and industrial point sources, which emit much larger quantities of ammonia to the atmosphere than previously thought.
The differentiation of the inner ear in the lamprey Lethenteron camtschaticum and hagfish Eptatretus burgeri sheds light on the evolution of the semicircular canals of jawed vertebrates.
A magnetically induced two-dimensional square lattice of merons and antimerons is observed in real space, along with its transformation into a hexagonal lattice of skyrmions at room temperature.
Orthogonal ribosomes are engineered in which the two subunits are stapled together in a way that limits association with endogenous subunits in cells, enabling the evolution of new functionality in the orthogonal ribosome.
Ice-core-derived melt records reveal that atmospheric warming has recently intensified Greenland ice-sheet surface melt and runoff to levels that are exceptional over at least the last 350 years.
The distinctive 20Ne/22Ne ratio in material thought to come from deep mantle plumes provides evidence for nebular gas as a source of volatiles in Earth’s interior.
Early results from the COSINE-100 experiment—designed to test a much-debated claim of the detection of a dark-matter signal—show no indications of dark matter, providing evidence against the previous claim.