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Busquets-García et al. provide a historical perspective of the discovery of endocannabinoid signalling and summarize the most recent findings on the role of endocannabinoids in the regulation of intracellular metabolism and its implications for whole-body homeostasis.
Gasser et al. provide a concise overview of the known metabolic functions of endogenous FGF1 and discuss its therapeutic potential after peripheral or central administration.
Perino and Schoonjans summarize the most recent literature on the receptor-mediated role of bile acid signalling in the control of peripheral and central energy homeostasis.