Table 3 - Diagnostic strategies for GER-related chronic cough
From the following article
Gastroesophageal reflux and chronic cough
Susan M. Harding
GI Motility online (2006)
doi:10.1038/gimo77
 Screen for GER and identify patients with clinically silent GER (see Table 2) |
| Begin 3-month empiric trial: |
| - Lifestyle modifications |
| - Twice daily proton pump inhibitor (PPI) 30–60 minutes before breakfast and dinner |
| - Consider adding prokinetic agent |
| Reassess cough response in 3 months |
| Order esophageal manometry and pH for nonresponders on GER therapy |
| Examine for other causes of chronic cough in nonresponders |
| Consider combined esophageal pH and impedance testing in nonresponders on medical therapy |
| Reduce PPI to once daily after cough resolution; some patients respond to H2-blockers |
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