Table 2 - Comparison of botulinum toxin A (BoT) injections to pneumatic dilation (PD) in achalasia
From the following article
Medical and endoscopic management of achalasia
Nonko Pehlivanov and Pankaj Jay Pasricha
GI Motility online (2006)
doi:10.1038/gimo52
| Author | Annese89 | Vaezi86 | Mikaeli36* | Ghoshal87 | Muehldorfer88 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| BoT | PD | BoT | PD | BoT | PD | BoT | PD | BoT | PD | |
*These authors used 200 U of Dysport. | ||||||||||
NR: not reported; LESP: lower esophageal sphincter pressure. | ||||||||||
Modified from Zhao and Pasricha.67 | ||||||||||
| Response rate | ||||||||||
| 1 month | 8/8 | 8/8 | 14/20 | 15/20 | 13/20 | 18/20 | 6/8 | 8/10 | 9/12 | 10/12 |
| 12 months | 6/8 | NR | 7/20 | 14/20 | 3/20 | 10/19 | 3/8 | 6/8 | NR | NR |
| Reduction in LESP | ||||||||||
| 1 month | -49% | -72% | -6 % | -66% | -24% | -26% | -53% | -62% | -44% | -51% |
| 12 months | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| Reduction in retention | ||||||||||
| 1 month | 47% | 59% | 33.6% | 50.2% | NR | NR | NR | NR | NR | NR |
| 12 months | NR | NR | 13.4% | 54.6% | NR | NR | NR | NR | NR | |
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