The Editors of Eye and Gene Therapy have put together this joint collection on gene therapy in the eye, to showcase some of the recent research in this field.

This is a special issue in a special year when we will reflect on the achievements (and challenges) of VISION 2020, a global WHO initiative that aimed to eliminate avoidable blindness. Much progress has been done to improve health outcomes in people with glaucoma but it is humbling to reflect on the burden of glaucoma, still a leading cause of blindness in the developed world and much of it preventable. The challenge of preventing blindness and providing glaucoma care in low-to-middle outcome countries are gigantic. In this special issue we have included some of the most relevant and exciting developments both in translational and clinical research. The efforts of many talented and dedicated individuals and organisations working towards prevention and treatment of glaucoma will continue to make a difference. We would like to thank all authors for their generous contributions. Anthony Khawaja and Augusto Azuara-Blanco

This collection highlights some of Eye’s published content contributed by authors from the US. Covering a range of topics on various fields within Ophthalmology, this Collection was curated by Eye’s Editor-in-Chief, Sobha Sivaprasad, and includes a selection of reviews and original research. Some of the reviews succinctly cover a large topic of interest while others provide perspectives on novel research areas or controversies. Original articles demonstrate diverse advances in research on disease mechanisms, therapeutics and basic science. The collection also includes an interesting article on Eponymous women in ophthalmology, emphasising syndromes with prominent eye manifestations named after female physicians!

An expert clinical advisory group named Action on nAMD met on 16 March 2018 in Birmingham, UK, to explore and discuss multidisciplinary practice initiatives and service developments in the management of nAMD.

Eye takes a look at the progress made in ophthalmology in the last 30 years with a special 30th anniversary collection.

This collection provides a wide spectrum of reviews on prevalent eye conditions in Asia. Areas of focus include new insights on Pachychoroid, the much awaited role of artificial intelligence in the screening of diabetic retinopathy, control of myopia, acute angle closure glaucoma and infectious and non-infectious disease of particular relevance in Asia.

Intravitreal Avastin - is it unlicensed, off-label, unlawful or cheap?

This selection of recently published manuscripts on age related macular degeneration (AMD) written by authors around the world covers a breadth of topics ranging from prediction models, risk factors including controversies in genetic testing, diagnostic dilemmas, evolution of terminologies defining the disease, evaluation of novel management options, treatment outcomes with currently available interventions and psychosocial impact of treatment burden.

A highlight of the Royal College of Ophthalmologists annual congress is the eponymous lectures. These are given by clinicians and scientists preeminent in their field. Eye is very pleased to bring together a selection of recent eponymous lectures in this web focus. These lectures discuss topics as wide ranging as health care in neglected populations to vision, eye disease and art. The topics are brilliantly discussed and provide a useful summary of the state of the art for the various topics in terms of current research and the next steps towards better therapies and treatments. We hope you will enjoy reading them.

This supplement, and the meeting on which it is based (Park Plaza, Vauxhall Road, London, 20th April 2016), were sponsored by Novartis.