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Infant gray mouse lemurs performed better when they were born to mothers fed with dairy fat vs. vegetable fat in a set of tasks involving motor synchronization, sensory perception, learning and memory, suggesting an earlier psychomotor and cognitive development.
We analyzed the organ of Corti motions, component by component. Outer hair cells exploit their supporting cells to boost vibrations of the upper part of the organ of Corti while minimally disturbing the basilar membrane.
Dynamic processes of bacterial genome amplification involving a non-replicable but inheritable circular DNA molecule encoding multiple drug resistance proteins.
A study suggests that TBC9, one of the Rab GTPase Activating Proteins, is crucial for early vesicular transport and inner membrane complex formation by regulating Rab2, Rab11A and Rab11B in Toxoplasma gondii.
Dynamic mode decomposition captures spatiotemporal patterns in neural activity such as human electrocorticographic signals. This study presents a novel method for vectorising the dynamic modes to increase the speed and accuracy of neural decoding.
Brain endothelial cells activate EGFR signaling in triple-negative breast cancer cells, promoting brain metastasis. DOCK4 is crucial for cancer cell extravasation to the brain, with EGFR activation driving cell elongation reversed by Afatinib.
This study demonstrates that adult zebra finches maintain song performance by preventing song changes through physical act of daily singing throughout their life.
This study presents the essential functions of the ZnF motif in sorting of the melanophilin protein and novel functions of melanophilin in dendritogenesis in melanocytes.
Designing a supervised latent factor framework for snRNA-seq human brain, the authors find distinct Alzheimer’s-predictive gene modules across celltypes, suggesting subcelltype disease progression trajectories.
Signal transducer and activator of transcription (STAT) is kept in an activated state in non-small cell lung cancer cells (NSCLC) through PRMT5 methylation, which also controls STAT’s transcriptional activity and tumour growth and cancer stem cell maintenance support.
ADAR2 KO mice are protected against several HFD–induced metabolic defects, show reduced hepatic lipid accumulation, improved hepatic insulin signaling, and increased pyruvate tolerance and glycogen synthesis, by activation of AMPK signaling pathways.
A differential scanning calorimetry study of Bacillus subtilis vitrification shows that perchlorate salts can lower the onset of intracellular vitrification, with implications for the low temperature limit of life in salt-rich subzero environments.
A human fMRI study shows that defensive cardiac states moderate the neural computations of reward and threat value underlying approach-avoidance arbitration.
This study shows that M2 macrophage-derived exosomes promote malignancy in ovarian cancer cells by delivering circTMCO3 and targeting the miR-515-5p/ITGA8 axis.
A Penicillium citrinum-associated pellet at mealybugs’ legs, which forms on mealybugs feeding on tomato and originates jointly from plant secretions and waxy filaments, provides multiple protections for mealybugs through suppressing pathogens and host defense.
Using flow cytometry and transcriptomic analyses, the authors characterize the functional diversity of B cell subsets in the lungs of patients with tuberculosis.
Over one-third of the sampled shorebirds along the East Asian-Australasian Flyway are facing Hg risk. Tringa genus in South China was at the highest risk. Feather Hg was best explained by feathers’ moulting region, while habitat preference, diet, and foraging stratum were less important.
By performing displacement experiments with Lamprologus ocellatus, we show evidence consistent with fish using path integration to navigate alongside other mechanisms: allothetic place cues and route recapitulation.
Population genomic and epigenomic study in a facultatively asexual plant indicates that natural selection can act on the controls of asexual reproduction during range expansion, which in turn might reduce genetic and epigenetic diversity in the population.