CANCER AND CELL SIGNALING
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Cancer biology and cell signaling have been traditionally strong areas for Cell Research. This focus presents a collection of selected articles from various issues, and includes some of the most recent exciting discoveries published in the journal
Reviews
Monoclonal antibodies as therapeutic agents in oncology and antibody gene therapy
Qi Zhang, Guihua Chen, Xinyuan Liu and Qijun Qian
Cell Res 17: 89–99; doi:10.1038/sj.cr.7310143
Mechanisms of cell immortalization mediated by EB viral activation of telomerase in nasopharyngeal carcinoma
Jun–Ping Liu, Lucy Cassar, Alex Pinto and He Li
Cell Res 16: 809–817; doi:10.1038/sj.cr.7310098
Hsp90 at the crossroads of genetics and epigenetics
Keith SK Wong and Walid A Houry
Cell Res 16: 742–749; doi:10.1038/sj.cr.7310090
The role of Toll-like receptors in non-infectious lung injury
Dianhua Jiang, Jiurong Liang, Yuhang Li and Paul W Noble
Cell Res 16: 693–701; doi:10.1038/sj.cr.7310085
Heme: a versatile signaling molecule controlling the activities of diverse regulators ranging from transcription factors to MAP kinases FREE
Sarah M Mense and Li Zhang
Cell Res 16: 681–692; doi:10.1038/sj.cr.7310086
Role of JNK activation in apoptosis: A double-edged sword FREE
Jing Liu and Anning Lin
Cell Res 15: 36–42; doi:10.1038/sj.cr.7290262
Wnt signaling in disease and in development FREE
Roel Nusse
Cell Res 15: 28–32; doi:10.1038/sj.cr.7290260
Activation and signaling of the p38 MAP kinase pathway FREE
Tyler Zarubin and Jiahuai Han
Cell Res 15: 11–18; doi:10.1038/sj.cr.7290257
WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension FREE
Bing-e Xu, Byung-Hoon Lee, Xiaoshan Min, Lisa Lenertz, Charles J Heise, Steve Stippec, Elizabeth J Goldsmith and Melanie H Cobb
Cell Res 15: 6–10; doi:10.1038/sj.cr.7290256
Original Articles
Arabidopsis AtBECLIN 1/AtAtg6/AtVps30 is essential for pollen germination and plant development FREE
Genji Qin, Zhiqiang Ma, Li Zhang, Shufan Xing, Xianhui Hou, Jie Deng, Jingjing Liu, Zhangliang Chen, Li-Jia Qu and Hongya Gu
Cell Res 17: 249–263; doi:10.1038/cr.2007.7
Cell polarity protein Par3 complexes with DNA–PK via Ku70 and regulates DNA double–strand break repair FREE
Longhou Fang, YiGuo Wang, Dan Du, Guang Yang, Tim Tak Kwok, Siu Kai Kong, Benjamin Chen, David J Chen and Zhengjun Chen
Cell Res 17: 100–116; doi:10.1038/sj.cr.7310145
Expression and regulation of IL–22 in the IL–17–producing CD4+ T lymphocytes
Yeonseok Chung, Xuexian Yang, Seon Hee Chang, Li Ma, Qiang Tian and Chen Dong
Cell Res 16: 902–907; doi:10.1038/sj.cr.7310106
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IB kinase (IKK)
Guoliang Qing, Pengrong Yan and Gutian Xiao
Cell Res 16: 895–901; doi:10.1038/sj.cr.7310109
Deficit of mitochondria–derived ATP during oxidative stress impairs mouse MII oocyte spindles
Xiao Zhang, Xue Qing Wu, Shuang Lu, Ying Lu Guo and Xu Ma
Cell Res 16: 841–850; advance online publication, September 19, 2006; doi:10.1038/sj.cr.7310095
A new interaction between Abi–1 and PIX involved in PDGF–activated actin cytoskeleton reorganisation
Fanny Campa, Nikolaus Machuy, Alexander Klein and Thomas Rudel
Cell Res 16: 759–770; doi:10.1038/sj.cr.7310091
Coordinated peak expression of MMP–26 and TIMP–4 in preinvasive human prostate tumor
Seakwoo Lee, Kevin K Desai, Kenneth A Iczkowski, Robert G Newcomer, Kevin J Wu, Yun–Ge Zhao, Winston W Tan, Mark D Roycik and Qing–Xiang Amy Sang
Cell Res 16: 750–758; doi:10.1038/sj.cr.7310089
Immunization with autologous T cells enhances in vivo anti-tumor immune responses accompanied by up-regulation of GADD45 FREE
Li Wang, Fang Du, Qi Cao, Huiming Sheng, Baihua Shen, Yan Zhang, Yingna Diao, Jingwu Zhang and Ningli Li
Cell Res 16: 702–712; doi:10.1038/sj.cr.7310083
Glycogen synthase kinase-3 positively regulates the proliferation of human ovarian cancer cell FREE
Aili Li and Long Mao
Cell Res 16: 671–677; doi:10.1038/sj.cr.7310078
Plant fertility defects induced by the enhanced expression of microRNA167 FREE
Peng Ru, Lin Xu, Hong Ma and Hai Huang
Cell Res 16: 457–465; doi:10.1038/sj.cr.7310057
The crystal structure of the non-liganded 14-3-3 protein: insights into determinants of isoform specific ligand binding and dimerization FREE
Anne Benzinger, Grzegorz M Popowicz, Joma K Joy, Sudipta Majumdar, Tad A Holak and Heiko Hermeking
Cell Res 15: 219–227; doi:10.1038/sj.cr.7290290