Clinical significance of MiRNA expression
Tumour MiRNAs - the focus of these articles is on changes during treatment, detection in urine or detection in tumours and how they relate to outcome and prognosis in a wide range of tumour types - pancreatic, prostate, bladder, colon cancer, melanoma, multiple myeloma and peripheral nerve sheath tumours. Though there is a major focus on genetic changes and the targeting of cancer treatment, microRNAs are another significant epigenetic mechanism for regulation in tumour biology that needs to integrated with the genetic profiles.
Identification of circulating microRNAs as diagnostic biomarkers for use in multiple myeloma Open
C I Jones, M V Zabolotskaya, A J King, H J S Stewart, G A Horne, T J Chevassut and S F Newbury
British Journal of Cancer 107: 1987-1996; Published online, 20 November 2012; doi:10.1038/bjc.2012.525
Clinical significance of miR-144-ZFX axis in disseminated tumour cells in bone marrow in gastric cancer cases Open
S Akiyoshi, T Fukagawa, H Ueo, M Ishibashi, Y Takahashi, M Fabbri, M Sasako, Y Maehara, K Mimori and M Mori
British Journal of Cancer 107: 1345-1353; Published online, 06 September 2012; doi:10.1038/bjc.2012.326
MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer Open
S Ali, H Saleh, S Sethi, F H Sarkar and P A Philip
British Journal of Cancer 107: 1354-1360; Published online, 28 August 2012; doi:10.1038/bjc.2012.383
The prognostic importance of miR-21 in stage II colon cancer: a population-based study Open
S Kjaer-Frifeldt, T F Hansen, B S Nielsen, S Joergensen, J Lindebjerg, F B Soerensen, R dePont Christensen and A Jakobsen
British Journal of Cancer 107: 1169-1174; Published online, 25 September 2012; doi:10.1038/bjc.2012.365
Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation Open
J S Hall, J Taylor, H R Valentine, J J Irlam, A Eustace, P J Hoskin, C J Miller and C M L West
British Journal of Cancer 107: 684-694; Published online, 17 July 2012; doi:10.1038/bjc.2012.294
An evaluation of urinary microRNA reveals a high sensitivity for bladder cancer Open
S Miah, E Dudziec, R M Drayton, A R Zlotta, S L Morgan, D J Rosario, F C Hamdy and J W F Catto
British Journal of Cancer 107: 123-128; Published online, 29 May 2012; doi:10.1038/bjc.2012.221
The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer Open
C B Lajer, E Garnæs, L Friis-Hansen, B Norrild, M H Therkildsen, M Glud, M Rossing, H Lajer, D Svane, L Skotte, L Specht, C Buchwald and F C Nielsen
British Journal of Cancer 106: 1526-1534; Published online, 03 April 2012; doi:10.1038/bjc.2012.109
High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer Open
R Hamano, H Miyata, M Yamasaki, K Sugimura, K Tanaka, Y Kurokawa, K Nakajima, S Takiguchi, Y Fujiwara, M Mori and Y Doki
British Journal of Cancer 106: 1415-1423; Published online, 20 March 2012; doi:10.1038/bjc.2012.90
miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients Open
Z Hagman, B S Haflidadóttir, J A Ceder, O Larne, A Bjartell, H Lilja, A Edsjö and Y Ceder
British Journal of Cancer 108: 1668-1676; Published online, 09 April 2013; doi:10.1038/bjc.2013.131
Changes in circulating microRNA levels associated with prostate cancer FREE
R J Bryant, T Pawlowski, J W F Catto, G Marsden, R L Vessella, B Rhees, C Kuslich, T Visakorpi and F C Hamdy
British Journal of Cancer 106: 768-774; Published online, 12 January 2012; doi:10.1038/bjc.2011.595
Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma FREE
H Konishi, D Ichikawa, S Komatsu, A Shiozaki, M Tsujiura, H Takeshita, R Morimura, H Nagata, T Arita, T Kawaguchi, S Hirashima, H Fujiwara, K Okamoto and E Otsuji
British Journal of Cancer 106: 740-747; Published online, 19 January 2012; doi:10.1038/bjc.2011.588
Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors FREE
Y Xu, T Brenn, E R S Brown, V Doherty and D W Melton
British Journal of Cancer 106: 553-561; Published online, 05 January 2012; doi:10.1038/bjc.2011.568
MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression Open
N Presneau, M Eskandarpour, T Shemais, S Henderson, D Halai, R Tirabosco and A M Flanagan
British Journal of Cancer 108: 964-972; Published online, 22 November 2012; doi:10.1038/bjc.2012.518
Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer Open
T Kawaguchi, S Komatsu, D Ichikawa, R Morimura, M Tsujiura, H Konishi, H Takeshita, H Nagata, T Arita, S Hirajima, A Shiozaki, H Ikoma, K Okamoto, T Ochiai, H Taniguchi and E Otsuji
British Journal of Cancer 108: 361-369; Published online, 17 January 2013; doi:10.1038/bjc.2012.546