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Cancer survivorship

Improving long-term outcomes in pediatric low-grade glioma

Nature Cancer volume 5, pages 533–535 (2024)Cite this article

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Low-grade glioma is a tumor type that affects the central nervous system, with favorable survival outcomes in children and adolescents. A study now provides insights into long-term mortality and morbidity associated with different treatments and demonstrates the multifaceted outcomes of adult survivors of childhood glioma.

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Fig. 1: Summary of study design and results.

References

  1. Ostrom, Q. T. et al. Neuro. Oncol. 16(suppl .1), x1–x36 (2015).

    Article  PubMed  Google Scholar 

  2. Krishnatry, R. et al. Cancer 122, 1261–1269 (2016).

    Article  PubMed  Google Scholar 

  3. Gnekow, A. K. et al. Neuro. Oncol. 14, 1265–1284 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. de Blank, P. M. K. et al. Nat. Cancer https://doi.org/10.1038/s43018-024-00733-0 (2024).

    Article  PubMed  Google Scholar 

  5. Merchant, T. E., Conklin, H. M., Wu, S., Lustig, R. H. & Xiong, X. J. Clin. Oncol. 27, 3691–3697 (2009).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Williams, N. L. et al. Am. J. Clin. Oncol. Cancer Clin. Trials 41, 307–312 (2018).

    Article  Google Scholar 

  7. Traunwieser, T. et al. Neuro-Oncol. Adv. 2, vdaa094 (2020).

    Article  Google Scholar 

  8. Yamanaka, R., Hayano, A. & Kanayama, T. Neurosurg.l Rev. 41, 719–731 (2018).

    Article  Google Scholar 

  9. Ajithkumar, T., Taylor, R. & Kortmann, R. D. Clin. Oncol. 31, 151–161 (2019).

    Article  CAS  Google Scholar 

  10. Ryall, S. et al. Cancer Cell 37, 569–583.e5 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Miklja, Z. et al. Neuro. Oncol. 21, 968–980 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Hargrave, D. R. et al. Clin. Cancer Res. 25, 7303–7311 (2019).

    Article  CAS  PubMed  Google Scholar 

  13. Bouffet, E. et al. N. Engl. J. Med. 389, 1108–1120 (2023).

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria

    Johannes Gojo

  2. Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria

    Matthias Preusser

Authors
  1. Johannes Gojo
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  2. Matthias Preusser
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Corresponding authors

Correspondence to Johannes Gojo or Matthias Preusser.

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Competing interests

M.P. has received honoraria for lectures, consultation or advisory board participation from the following for-profit companies: Bayer, Bristol-Myers Squibb, Novartis, Gerson Lehrman Group (GLG), CMC Contrast, GlaxoSmithKline, Mundipharma, Roche, BMJ Journals, MedMedia, Astra Zeneca, AbbVie, Lilly, Medahead, Daiichi Sankyo, Sanofi, Merck Sharp & Dome, Tocagen, Adastra, Gan & Lee Pharmaceuticals, Janssen, Servier, Miltenyi, Böhringer-Ingelheim, Telix and Medscape. J.G. has received honoraria for lectures, consultation or advisory board participation from the following for-profit companies: Novartis and Roche.

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Gojo, J., Preusser, M. Improving long-term outcomes in pediatric low-grade glioma. Nat Cancer 5, 533–535 (2024). https://doi.org/10.1038/s43018-024-00741-0

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