A flexible open-top light-sheet microscope has been developed that can perform deep three-dimensional imaging on all clearing protocols with low and high optical resolution.
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References
Glaser, A. K. et al. Nat. Methods https://doi.org/s41592-022-01468-5 (2022).
Richardson, D. S. & Lichtman, J. W. Cell 162, 246–257 (2015).
McGorty, R. et al. Opt. Express 23, 16142–16153 (2015).
Barner, L. A., Glaser, A. K., True, L. D., Reder, N. P. & Liu, J. T. C. Opt. Lett. 44, 4451–4454 (2019).
Barner, L. A., Glaser, A. K., Huang, H., True, L. D. & Liu, J. T. C. Biomed. Opt. Express 11, 6605–6619 (2020).
Migliori, B. et al. BMC Biol. 16, 57 (2018).
Tanaka, N. et al. Nat. Biomed. Eng. 4, 875–888 (2020).
Ueda, H. R. et al. Nat. Rev. Neurosci. 21, 61–79 (2020).
Almagro, J., Messal, H. A., Zaw Thin, M., van Rheenen, J. & Behrens, A. Nat. Rev. Cancer 21, 718–730 (2021).
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Kanatani, S., Uhlén, P. Imaging cleared tissues made easy. Nat Methods 19, 527–529 (2022). https://doi.org/10.1038/s41592-022-01424-3
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DOI: https://doi.org/10.1038/s41592-022-01424-3
