A deep-learning-based tool and a large ground truth dataset enable spike inference from calcium imaging data acquired in a variety of experimental conditions.
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Research paper
Rupprecht, P. et al. A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging. Nat. Neurosci. 24, 1324–1337 (2021).
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Vogt, N. Spike inference with CASCADE. Nat Methods 18, 1147 (2021). https://doi.org/10.1038/s41592-021-01295-0
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DOI: https://doi.org/10.1038/s41592-021-01295-0