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MASS SPECTROMETRY

Mass spectrometry comes of age for subcellular organelles

Technological innovations in optical object recognition and high-throughput ultrasensitive mass spectrometry are enabling subcellular metabolomics and peptidomics, providing unprecedented opportunities to study small-molecule mediators of cellular function with important implications in health and disease.

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Fig. 1: Mass spectrometry of organelles.

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Correspondence to Peter Nemes.

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Nemes, P. Mass spectrometry comes of age for subcellular organelles. Nat Methods 18, 1157–1158 (2021). https://doi.org/10.1038/s41592-021-01287-0

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