Controlled interactions between macromolecules are fundamental regulatory layers. Hijacking these circuits via proximity-inducing small molecules offers many therapeutic opportunities. The organizers, Georg Winter and Cristina Mayor-Ruiz, report on the latest trends in this emerging field discussed at the 39th IRB-BioMed Conference in Barcelona.
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G.E.W. is a scientific founder and shareholder of Proxygen and Solgate. His lab has received research funding from Pfizer. C.M.-R. is part of the scientific advisory board of Nostrum Biodiscovery. Her lab has received or receives sponsored research support from Almirall and Aelin Tx.
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Winter, G.E., Mayor-Ruiz, C. Proximity-inducing pharmacology. Nat Chem Biol 20, 13–14 (2024). https://doi.org/10.1038/s41589-023-01492-2
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DOI: https://doi.org/10.1038/s41589-023-01492-2