Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Post-translational modification

Greasy proteins made easy

Nature Chemical Biology volume 20, pages 4–5 (2024)Cite this article

Subjects

Protein lipidation is an important post-translational modification that can be difficult to study. New amino acids with side chains that mimic naturally occurring lipid modifications stand to facilitate the study of lipidated proteins.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Methods of protein lipidation.

References

  1. Ding, W. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-023-01400-8 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Walsh, C. T., Garneau-Tsodikova, S. & Gatto, G. J. Angew. Chem. Intl Edn 44, 7342–7372 (2005).

    Article  CAS  Google Scholar 

  3. Young, D. D. & Schultz, P. G. ACS Chem. Biol. 13, 854–870 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Chen, J. & Tsai, Y.-H. J. Mol. Biol. 434, 167424 (2022).

    Article  CAS  PubMed  Google Scholar 

  5. Jiang, H. et al. Chem. Rev. 118, 919–988 (2018).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Molecular Sciences and The Biodesign Institute of Molecular Design and Biomimetics, Arizona State University, Tempe, AZ, USA

    Jeremy H. Mills

Authors
  1. Jeremy H. Mills
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jeremy H. Mills.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mills, J.H. Greasy proteins made easy. Nat Chem Biol 20, 4–5 (2024). https://doi.org/10.1038/s41589-023-01437-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41589-023-01437-9

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing