Studies of the microbiome–host interaction are uncovering the metabolic mutual crosstalk between host tissues and gut microbiota. Hepatic glutamine synthetase takes part in this interaction by metabolizing a bacterial substance and producing a molecule with interesting clinical potential.
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Mazzone, M., Castegna, A. A collaborative synthetase. Nat Chem Biol 19, 255–256 (2023). https://doi.org/10.1038/s41589-022-01171-8
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DOI: https://doi.org/10.1038/s41589-022-01171-8