Optogenetic and thermogenetic tools have been limited to applications for single-state control of cellular processes. A single-component optogenetic tool was found to act as both a temperature sensor and a photoreceptor, enabling multi-state control of developmental signaling.
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Wilson, M.Z. Optogenetics in the hot seat. Nat Chem Biol 18, 118–119 (2022). https://doi.org/10.1038/s41589-021-00928-x
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DOI: https://doi.org/10.1038/s41589-021-00928-x