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PRE-ECLAMPSIA

The pathogenesis of pre-eclampsia in kidney donors

Kidney donation and chronic kidney disease are associated with an increased risk of pre-eclampsia. A recent study in pregnant uninephrectomized mice provides new insights into the mechanisms that underlie these associations and potential therapeutic strategies.

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Fig. 1: Complicated pregnancies increase the risk of CKD and pre-eclampsia in the next generation.

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Correspondence to Giorgina Barbara Piccoli.

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Piccoli, G.B., Orozco-Guillén, O.A. The pathogenesis of pre-eclampsia in kidney donors. Nat Rev Nephrol 19, 7–8 (2023). https://doi.org/10.1038/s41581-022-00646-0

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